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Scholarly Interest Report
         
Jianpeng Ma
Professor
Professor of Bioengineering
 
e-mail:jpma@rice.edu
 
  • B.S. (1985), Physical Chemistry, Fudan University, Shanghai, PRC
  • Ph.D. (1996), Chemistry, Boston University, Boston, Massachusetts
 
Primary Department
   Department of Bioengineering
Picture
 
Other Affiliations
 
  • Baylor College of Medicine
  •  
    Websites
     Jianpeng Ma
     Ma Group Home Page
     
    Research Areas
     Research Interests: The main focus of research is on computational study of structure-function relationship of proteins.
     
    Research Statement
     

    The projects in our research group aim at the frontier of modern computational biophysics and structural biology. There are three major research directions:



    • Molecular Dynamics (MD) Simulation of Supermolecular Complexes
      Large-scale conformational transitions in protein structures play an important role in a variety of cellular processes. Understanding such transitions is one of the central tasks of modern biophysics and structural biology. Among all the available structural and biophysical methods, computer simulation is a powerful method that allows one to model the motions of proteins in atomic details.

      The research projects primarily focus on systems that involve coordinated large domain movements. Our recent work on the molecular chaperonin GroEL provided a paradigm for this type of research, and it also demonstrates that molecular dynamics simulation has come into an age of realistically modeling very large protein complexes.

    • Structural Refinement for X-ray Crystallography and EM Reconstruction
      In recent history, application of molecular dynamics simulation has significantly improved the structural refinement in x-ray crystallography. However, as structural biology moves towards new challenges from systems such as motors in which parts of the structures are inherently mobile, it is increasingly important to employ more advanced computational methods to model such motions in structure refinement.

      Another important trend in structural biology is the fast development of Electron Microscopy (EM) reconstruction, which is now able to deliver 6-7 E resolution for systems that are difficult to handle by conventional NMR and x-ray crystallography. A combination of EM reconstruction and computational modeling harbors the hope for future realization of atomic resolution measurement. Our goal is to use and develop the state-of-the-art simulation methods to meet the demand of frontier experimental measurement.

    • Computer-Aided Drug-Design
      As a part of bioinformatics, computer-aided drug design has been an exploding field in recent years.

      The research of our group will use both the structure-based approaches and ligand-based approaches such as QSAR (Quantitative Structure-Function Relationship) methods. Several important systems are being targeted.

     
    Selected Publications
     Refereed articles
     

    Jingwei Weng, Jianpeng Ma, Kangnian Fan and Wenning Wang "The Conformational Coupling and Translocation Mechanism of Vitamin B12 ATP-Binding Cassette Transporter BtuCD." Biophysics Journal, 94 (2008) : 612–621.

     
     

    Mingyang Lu and Jianpeng Ma "A Minimalist Network Model for Coarse-Grained Normal Mode Analysis and Its Application to Biomolecular X-Ray Crystallography." Proceedings of the National Academy of Sciences, USA, 105 (2008) : 15358-15363.

     
     

    Mingyang Lu, Athanasios D. Dousis and Jianpeng Ma "OPUS-PSP: An Orientation-dependent Statistical All-atom Potential Derived from Side-chain Packing." Journal of Molecular Biology, 376 (2008) : 288-301.

     
     

    Mingyang Lu, Athanasios D. Dousis and Jianpeng Ma "OPUS-Rota: A Fast and Accurate Method for Side-chain Modeling." Protein Science, 17 (2008) : 1576-1585.

     
     

    Qinghua Wang, Feng Cheng, Mingyang Lu, Xia Tian and Jianpeng Ma "Crystal Structure of Unliganded Influenza B Virus Hemagglutinin." Journal of Virology, 82 (2008) : 3011-3020.

     
     

    Billy K. Poon, Xiaorui Chen, Mingyang Lu, Nand K. Vyas, Florante A. Quiocho, Qinghua Wang and Jianpeng Ma "Normal Mode Refinement of Anisotropic Thermal Parameters for Supramolecular Complexes at Moderate Resolution of X-ray Diffraction." . Proc. Natl. Acad. Sci., 104 (2007) : 7869-7874.

     
     

    Cheng Zhang, Jianpeng Ma "Simulation via direct computation of partition functions." Phys. Tev. E Stat. Nonlin. Soft Matter Phys. (2007)

     
     

    Feng Cheng, Qinghua Wang, Mingzhi Chen, Florante A. Quiocho & Jianpeng Ma "Molecular Docking Study of the Interactions between the Thioesterase Domain of Human Fatty Acid Synthase and Its Ligands. Proteins: Structure, Function, and Bioinformatics." In Press

     
     

    Quinghua Wang, Xia Tian, Xiaorui Chen, Jianpeng Ma "Structural Basis for Receptor Specificity of Influenza B Virus Hemagglutinin." Proc. Natl. Acad. Sci. (2007) : 16874-16879.

     
     

    Xiaorui Chen, Billy K. Poon, Athanasios Dousis, Qinghua Wang & Jianpeng Ma "Normal Mode Refinement of Anisotropic Thermal Parameters for Potassium Channel KcsA at 3.2- Crystallographic Resolution." Structure, 15 (2007) : 955-962.

     
     

    Yinghao Wu, Mingyang Lu, Mingzhi Chen, Jialin Li & Jianpeng Ma "OPUS-Ca: A Knowledge-based Potential Function Requiring Only Ca Positions." Prot. Sci., 16 (2007) : 1449-1463.

     
     

    Chen M, Wilson CJ, Wu Y, Wittung-Stafshede P, Ma J "Correlation between Protein Stability Cores and Protein Folding Kinetics: A Case Study on Pseudomonas aeruginosa Apo-Azurin." Structure, 14 (2006) : 1401-1410.

     
     

    Mingyang Lu, Billy Poon, and Jianpeng Ma "A New Method for Coarse-grained Elastic Normal Mode Analysis." J Comp Theor Chem, 2 (2006) : 464-471.

     
     

    Rajesh R. Singh, Kumaralal Kaluarachchi, Mingzhi Chen, Suresh K. Rayala, Seetharaman Balasenthil, Jianpeng Ma, and Rakesh Kumar "Solution Structure and Antiestrogenic Activity of the Unique C-terminal, NR-box Motif-containing Region of MTA1s." J. Biol. Chem., 281 (2006) : 25612-25621.

     
     

    Yifei Kong, Jianpeng Ma, Martin Karplus, and William N. Lipscomb "The Allosteric Mechanism of Yeast Chorismate Mutase: A Dynamics Analysis." J. Mol. Biol, 356 (2006) : 237-247.

     
     Articles
     

    Mingyang Lu and Jianpeng Ma (2011). Normal mode analysis with molecular geometry restraints: Bridging molecular mechanics and elastic models. Arch Biochem Biophys. 508: 64-71.

     
     

    B. K. Muralidhara, Mingzhi Chen, Jianpeng Ma, and Pernilla Wittung-Stafshede (2005) "Effect of Inorganic Phosphate on FMN Binding and Loop Flexibility in Desulfovibrio desulfuricans Apo-falvodoxin." J. Mol. Biol., 349: 87-97.

     
     

    Jianpeng Ma (2005) "Usefulness and Limitations of Normal Mode Analysis in Modeling Dynamics of Biomolecular Complexes." Structure, 13: 373-380.

     
     

    L. Elchlnger, ...., Jianpeng Ma et al. (2005) "The Genome of the Social Amoda Dictyostelium Discoideum." Nature, 435: 43-57.

     
     

    Martin Karplus, Yi Qin Gao, Jianpeng Ma, Arjan van der Vaart, and Wei Yang (2005) "Protein Structural Transitions and Their Functional Role." Phil. Trans. R. Soc., 363: 331-356.

     
     

    Mingyang Lu and Jianpeng Ma (2005) "The Role of Shape in Determining Molecular Motions." Biophys. J., 89: 2395-2401.

     
     

    Sergei Trakhanov, Nand K. Vyas, Hartmut Luecke, David M. Kristensen, Jianpeng Ma, and Florante A. Quiocho (2005) "Ligand-free and -bound Structures of the Binding Protein (LivJ) of the Escherichia coli ABC Leucine/Isoleucine/Valine Transport System: Trajectory and Dynamics of the Interdomain Rotation and Ligand Specificity." Biochemistry, 44: 6597-6608.

     
     

    Yechun Xu, Jianhua Shen, Xiaomin Luo, Weiliang Zhu, Kaixian Chen, Jianpeng Ma and Hualiang Jiang (2005) "Conformational Transition of Amyloid beta-peptide." Proc. Natl. Acad. Sci. USA., 102: 5403-5407.

     
     

    Yinghao Wu, Mingzhi Chen, Mingyang Lu, Qinghua Wang, and Jianpeng Ma (2005) "Determining Protein Topology from Skeletons of Secondary Structures." J. Mol. Biol, 350: 571-586.

     
     

    Yinghao Wu, Xia Tian, Mingyang Lu, Mingzhi Chen, Qinghua Wang and Jianpeng Ma (2005) "Folding of Small Helical Proteins Assisted by Small Angle X-ray Scattering Profiles." StructureIn Press

     
     

    Arjan van der Vaart, Jianpeng Ma and Martin Karplus "The Unfolding Action of GroEL on A Protein Substrate." Biophys. J., 87 (2004) : 562-573.

     
     

    Jacob Brink, Steven J. Ludtke, Yifei Kong, Salih J. Wakil, Jianpeng Ma and Wah Chiu "Experimental Verification of Conformational Variation of Human Fatty Acid Synthase as Predicted by Normal Mode Analysis." Structure, 12 (2004) : 185-191.

     
     

    Jianpeng Ma "New Advances in Normal Mode Analysis of Supermolecular Complexes and Applications to Structural Refinement." Curr. Prot. Pept. Sci, 5 (2004) : 119-123.

     
     

    Qiang Cui, Guohui Li, Jianpeng Ma and Martin Karplus "A Normal Mode Analysis of Structural Plasticity in the Biomolecular Motor F1-ATPase." J. Mol. Biol, 340 (2004) : 345-372.

     
     

    Terence C. Flynn and Jianpeng Ma "Differential Flexibility of Bacterial Flagellar Hook and Filament by Quantized Elastic Deformational Model." Biophys. J, 86 (2004) : 3204-3210.

     
     

    Yifei Kong, Xing Zhang, Timothy S. Baker and Jianpeng Ma "A Structural-informatics Approach for Tracing b-sheets: Building Pseudo-Ca-traces for b-strands in Intermediate-Resolution Density Maps." J. Mol. Biol, 339 (2004) : 117-130.

     
     

    Yinghao Wu and Jianpeng Ma "Normal-mode-based Refinement of an F-actin Model Against Fibre Diffraction Data." Fibre Diffraction Review, 12 (2004) : 25-28.

     
     

    Yinghao Wu and Jianpeng Ma "Refinement of F-actin Model Against Fibre Diffraction Data by Long range Normal Modes." Biophys. J., 86 (2004) : 116-124.

     
     Book chapters
     

    Jianpeng Ma "Applications of Normal Mode Analysis in Structural Refinement of Supramolecular Complexes." Normal Mode Analysis: Theory and Applications to Biological and Chemical SystemsIn Press

     
     

    Jianpeng Ma "Simulating, Refining and Modeling Protein Structures at Intermediate Resolutions." Computational Methods for Protein Structure Prediction and ModelingIn Press

     
     

    Jianpeng Ma "Supramolecular Complexes: Structure, Motion and Refinement." Encyclopedia of Molecular Cell Biology and Molecular Medicine (EMCBMM), 2nd EditionIn Press

     
     Other
     

    Christian T. Farrar, Jianpeng Ma, Martin Karplus, Alfred G. Redfield, David J. Singel, and Christopher J. Halkides "Structural Changes Induced in p21 upon GAP-334 Complexation as Probed by ESEEM Spectroscopy and Molecular Dynamics." Structure (2000)

     
     

    Jianpeng Ma and Martin Karplus "Ligand Induced Conformational Changes in ras p21: A Normal Mode and Energy Minimization Analysis." J. Mol. Biol. (1997) : 274, 114.

     
     

    Jianpeng Ma and Martin Karplus "Molecular Switch in Signal Transduction: Reaction Paths of the Conformational Changes in ras p21." Proc. Natl. Acad. Sci. (1997) : 94, 11905.

     
     

    Jianpeng Ma and Martin Karplus "The Allosteric Mechanism of the Chaperonin GroEL: A Dynamic Analysis." Proc. Natl. Acad. Sci. USA (1998) : 95, 8502.

     
     

    Jianpeng Ma, Paul B. Sigler, Zhaohui Xu and Martin Karplus "A Dynamic Model for the Allosteric Mechanism of GroEL." J. Mol. Biol., 302 (2000) : 303.

     
     

    Jianpeng Ma, Shuanghong Huo and John E. Straub "Molecular Dynamics Simulation Study of the B- states of Solvated Carbon Monoxy-myoglobin." J. Am. Chem. Soc., 119 (1997) : 2541.

     
     

    Jianpeng Ma, Xiaofeng Zheng, Georg Schnappauf, Gerhard Braus, Martin Karplus and William N. Lipscomb "Yeast Chorismate Mutase in the R State: Simulations of the Active Site." Proc. Natl. Acad. Sci. USA (1998) : 95, 14640.

     
     

    William N. Lipscomb, Gerhard Braus and Jianpeng Ma "Activity, Regulation and Molecular Dynamics in Yeast Chorismate Mutase." Proc. NATO Adv. Study Ins. (1999) : 302.

     
    Presentations
     Conference Committee Member
     

    "Deriving Protein Topology from Low-resolution Experimental Data." 230th ACS National Meeting, Washington DC. (August 28-September 1, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Multiscale Computational Simulation Workshop, Snowbird, Utah. (October 4-7, 2005)

     
     Invited Talks
     

    "“A Novel Empirical Potential Function and A Monte Carlo Sampling Technique”." ABCS Workshop on Bioinformatics, Computational Biology and Systems Biology, Texas A&M University - College Station, TX. (February 22-23, 2008)

     
     

    "“A Novel Empirical Potential Function and A Monte Carlo Sampling Technique”." Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, TX. (March 3, 2008)

     
     

    "“A Novel Empirical Potential Function and A Monte Carlo Sampling Technique”." Bioinformatics 2008 Conference, Warsaw, Poland. (April 24-27, 2008)

     
     

    "“A Novel Empirical Potential Function and A Monte Carlo Sampling Technique”." 2008 APS March Meeting, New Orleans, LA. (March 10-14, 2008)

     
     

    "“A Novel Empirical Potential Function and A Monte Carlo Sampling Technique”." Department of Chemistry, Duke University, Durham, NC. (March 18, 2008)

     
     

    "“Improving Structures Of Supramolecular Complexes And Membrane Proteins At Lower Resolutions Of X-Ray Diffraction”." 4th International Symposium on Structural Analysis of Supramolecular Assemblies by Hybrid Methods, Lake Tahoe, CA. (March 12-16, 2008)

     
     

    "“Improving Structures of Supramolecular Complexes and Membrane Proteins at Moderate Resolutions of X-ray Diffraction”." 52nd Biophysical Society Annual Meeting, Long Beach, CA. (February 2-6, 2008)

     
     

    "“Multi-scale modeling of biomolecular complexes”." “Characterizing Landscape: From Biomolecules to Cellular Networks” Workshop, Telluride Science Research Center, Telluride, CO. (July 6-11, 2008)

     
     

    "“Multi-scale modeling of biomolecular complexes”." Annual CHARMM Meeting, Harvard University, Cambridge, MA. (July 11-12, 2008)

     
     

    "“Multi-scale modeling of biomolecular complexes”,." “Algorithmic Development on Enhanced Sampling” Workshop, Telluride Science Research Center, Telluride, CO. (July 14-18, 2008)

     
     

    "“New algorithms for improving structures at lower resolutions of X-ray diffraction”." "New Algorithms in Macromolecular Crystallography and Electron Microscopy” Workshop, Leiden, The Netherlands. (May 13-17, 2008)

     
     

    "“New algorithms for improving structures at lower resolutions of X-ray diffraction”." The 6th International Symposium for Chinese Medicinal Chemists, Chinese Academy of Science, Shanghai, P.R. China. (July 28-August 1, 2008)

     
     “New computational algorithms for multiscale simulation and modeling”, in Multiscale Modeling in Biophysics, Division of Physical Chemistry, The 235th ACS National Meeting
     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." 13th Texas Protein Folders Meeting, Camp Allen, Navasota, Texas. (June 3-5, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." 40th IUPAC Congress, Beijing, P. R. China. (August 14-19, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Symposium To Celebrate William Lipscomb's 85th Birthday, Shanghai, P. R. China. (August 9-12, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Xi'an Jiaotong Univeristy, Xi'an, P. R. China. (August 8, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Bioinformatics Conference, Jilin University, Changchun, P. R. China. (July 6-9, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Symposium on Protein Folding, Function, and Dynamics, Peking University, Beijing, P. R. China. (July 4-7, 2005)

     
     

    "Deriving Protein Topology from Low-resolution Experimental Data." Lecture Series to Celebrate Centennial Anniversary of Fudan University, Fudan University, Shanghai, P. R. China. (July 1, 2005)

     
     

    "New Advances in Normal Mode Analysis." 7th Congress of World Association of Theory-orientated Chemists, Cape Town, South Africa. (January 16-22, 2005)

     
     

    "Simulating, Refining and Modeling Supermolecular Complexes at Multi-resolution and Multi-length Scales." New Advance in Drug Design, Hainan, China. (January 1-3, 2005)

     
     

    "Simulating, Refining and Modeling Supramolecular Complexes at Multi-resolution and Multi-length Scales." Frontier in Molecular Dynamics Simulation, Georgia Institute of Technology, Atlanta, Georgia. (April 28-29, 2005)

     
     

    "Simulating, Refining and Modeling Supramolecular Complexes at Multi-resolution and Multi-length Scales." Department of Biology, Georgia Institute of Technology, Atlanta, Georgia. (March 16, 2005)

     
     

    "Simulating, Refining and Modeling Supramolecular Complexes at Multi-resolution and Multi-length Scales." University of Southern California, Los Angels, California. (February 25, 2005)

     
     Lectures
     

    "A Multiscale Approach for Protein Structure Prediction and Modeling." 62nd SouthWest Regional Meeting of the American Chemical Society, Houston, Texas. (October 21-22, 2006)

     
     

    "A Multiscale Approach for Protein Structure Prediction and Modeling”, in Seminar series in Non-linear Physics." University of Houston, Houston, Texas.. (September 18, 2006)

     
     

    "A Multiscale Approach for Protein Structure Prediction and Modeling, in VII Spanish Bioinformatics Symposium." Zaragoza, Spain. (November 20-22, 2006)

     
     

    "Computationally Determining Tertiary Topology of Proteins from Small Angle X-ray Scattering (SAXS) Profiles." 3rd International Conference on Structural Analysis of Supramolecular Assemblies by Hybrid Methods, Lake Tahoe, California. (March 15-19, 2006)

     
     

    "New Methods for Simulating, Refining and Modeling Su-pramolecular Complexes at Multi-resolution and Multi-length Scales." 14th Texas Protein Folder's Meeting", Camp Allen, Navasota, Texas. (April 21-23, 2006)

     
     

    "New Methods for Simulating, Refining and Modeling Su-pramolecular Complexes at Multi-resolution and Multi-length Scales." Rigidity, Flexibility, and Motion in Biomolecules" Workshop, Tempe, Arizona. (May 14-17, 2006)

     
     

    "New Methods for Simulating, Refining and Modeling Su-pramolecular Complexes at Multi-resolution and Multi-length Scales." University of Wisconsin at Madison, Wisconsin. (May 17-21, 2006)

     
     

    "New Methods for Simulating, Refining and Modeling Su-pramolecular Complexes at Multi-resolution and Multi-length Scales." San Francisco, California. (April 1-5, 2006)

     
     

    "SAXS-assisted Protein Folding in FiberNet: Fiber Diffrac-tion Workshop." Fall Creek Falls Park, Pikeville, TN. (August 6-9, 2006)

     
     

    "SAXS-assisted Protein Folding”." XIII International Conference on Small Angle Scattering, Kyoto, Japan. (July 9-13, 2006)

     
     Other
     

    "Allosteric Mechanism of the Chaperonin GroEL: A Dynamic Analysis." PMMB Workshop: Doing Science at the Interface, UC, Berkely, California. (June 1998)

     
     

    "Dynamic Analysis of the Allosteric Mechanism of the Molecular Chaperonin GroEL." Protein Society Meeting, Boston, Massachusetts. (July 1999)

     
     

    "Molecular Switches in Signal Transduction Pathway." Specificity in Ras and Rhomediated Signaling Events, Madrid, Spain. (October 1999)

     
     

    "Reaction Path Determination of Large Scale Conformational Change in ras p21." 17th International Congress of Biochemistry and Molecular Biology, San Francisco, CA. (August 1997)

     
     

    "Triggers for the conformational changes in ras p21." Protein Society Meeting, Boston, Massachusetts. (July 1997)

     
    Editorial Positions
     Member of the Editorial Board, Current Protein and Peptide Science. (2008 - 2008)

     Member of the Editorial Board, Current Protein and Peptide Science. (2006 - 2006)

     Other, Current Protein and Peptide Science. (2005 - 2005)

     Other, Proceedings of the National Academy of Sciences. (2005 - 2005)

     Other, Biophysical Journal. (2005 - 2005)

     Other, Chemical Physics Letters. (2005 - 2005)

     Other, Proteins: Structure, Function, and Genetics. (2005 - 2005)

     Other, Chemistry & Biology. (2005 - 2005)

     Other, Journal of Molecular Biology. (2005 - 2005)

     Other, Journal of Structural Biology. (2005 - 2005)

     Other, Journal of Biomedical Nanotechnology. (2005 - 2005)

     Other, FEBS Letters. (2005 - 2005)

     Other, Structure. (2005 - 2005)

     Other, Journal of Physical Chemistry. (2005 - 2005)

     Other, Journal of Physics D. (2005 - 2005)

     Other, Mathematical Biosciences. (2005 - 2005)

     Other, PLoS Computational Biology. (2005 - 2005)

     Other, Bioorganic and Medicinal Chemistry. (2005 - 2005)

     Other, Journal of Chemical Theory and Computation. (2005 - 2005)

     Other, Annals of Biomedical Engineering. (2005 - 2005)

    Supervised Theses & Dissertations
     Hui Yao, Committee Member. (Committee Member)

     Kexin Huang, Committee Member. (Committee Member)

     William J. Salerno, Committee Member. (Committee Member)

     Committee Member. (Committee Member)

     Wei Dai, Committee Member. (Committee Member)

     Yue Liu, Committee Member. (Committee Member)

    Awards, Prizes, & Fellowships
     Faculty Early Career Development (CAREER) Award, National Science Foundation, (2003-2008)

     Recipient of the Faculty Early Career Development (CAREER) Award, (2003-2008)

     Faculty Early Career Development (CAREER) Award, National Science Foundation (2003-2008)

     Award for Distinguished Young Scholars Abroad, Chinese National Natural Science Foundation (2003-2005)

     Recipient of the Award, Chinese National Natural Science Foundation, P.R. China (2003-2005)

     Awarded, The Welch Foundation (2004)

     Awarded, National Science Foundation (2003-2008)

    Positions Held
     Member, American Chemical Society. (2011 - 2011)

     Member, American Crystallographic Association. (2011 - 2011)

     Member, Protein Society. (2011 - 2011)

     Member, American Physical Society. (2011 - 2011)

     Member, Biophysical Society. (2011 - 2011)

     Member, Biomedical Engineering Society. (2011 - 2011)

     Member, Protein Society. (2004 - 2004)

     American Chemical Society. (2006 - 2006)

     Member, American Chemical Society. (2008 - 2008)

     Protein Society. (2006 - 2006)

     Member, American Chemical Society. (2004 - 2004)

     Member, Protein Society. (2008 - 2008)

     Biophysical Society. (2006 - 2006)

     Member, Biophysical Society. (2004 - 2004)

     Member, Biophysical Society. (2008 - 2008)

     Member, Biomedical Engineering Society. (2004 - 2004)

     Biomedical Engineering Society. (2006 - 2006)

     Member, Biomedical Engineering Society. (2008 - 2008)

     Member, American Crystallographic Association. (2008 - 2008)

     American Crystallographic Association. (2006 - 2006)

     Member, American Crystallographic Association. (2004 - 2004)

     Associate Professor, BCM. (2006 - 2006)

     Member, American Physical Society. (2008 - 2008)

     Participating Faculty Member, BCM. (2006 - 2006)

     Adjunct Associate Professor, University of Texas M.D. Anderson Cancer Center. (2006 - 2006)

     Guest Professor, Fudan University. (2006 - 2006)

     Guest Professor, Eastern China University of Science and Technology. (2006 - 2006)

     Adjunct Associate Professor, University of Texas - Houston Health Science Center. (2006 - 2006)

     Associate Professor, Department of Bioengineering, Rice University. (2006 - 2006)

     Guest Professor, Shanghai Institute of Materia Medica, Chinese Academy of Sciences. (2006 - 2006)

     Fellow of Rice Quantum Institute, Rice University. (2006 - 2006)

     Participating Faculty Member of Keck Center for Computational and Structural Biology. (2006 - 2006)

     Participating Faculty Member of the Houston Area Molecular Biophysics Predoctoral (Ph.D.) Training Program (HAMBP). (2006 - 2006)

     Participating Researcher of Center for Biological and Environmental Nanotechnology (CBEN),, Rice University. (2006 - 2006)