Rice
FIS

FIS image header
  •  
  •  
  •  
  •  
  •  
Download 
Scholarly Interest Report
         
Michael Diehl
Associate Professor
Associate Professor of Bioengineering and Chemistry
 
e-mail:diehl@rice.edu
 
  • Ph.D. Physical Chemistry (2002) University of California, Los Angeles
  • Beckman Senior Research Fellow Biophysics, Bioengineering (2002-2005) California Institute of Technology
  • B.S. Chemistry (1997) The College of New Jersey, New Jersey
 
Primary Department
   Department of Bioengineering
Picture
 
Department Affiliations
 
  • Department of Chemistry
  •  
    Websites
     Diehl Laboratory
     Diehl Lab
     Michael R. Diehl
     
    Research Areas
     Biomolecular Imaging, Biophysics, Cellular Engineering, Protein and Molecular Bioengineering, Immunology, Cancer
     
    Research Interests 30-JAN-2018
     

    The Diehl laboratory’s research is deeply rooted in the development of synthetic, experimental and computational approaches to investigate protein coordination within multi-component complexes and protein networks. While focused on frontier problems in cancer and immunology, their research integrates advances from physical and biological chemistry, nanomaterials engineering, chemical biology, cellular engineering synthetic biology and single-molecule biophysics, and has facilitated the development of model protein complexes, engineered cell platforms, and molecular imaging technologies that provide new opportunities to dissect dynamic interactions among proteins within large, multicomponent and intrinsically disordered complexes. Their protein and cellular engineering approaches have enabled detailed mechanistic analyses of protein interactions and cooperativity. To date, this work has led to a new and deep fundamental understanding of mechanisms underlying collective functions of cytoskeletal motor proteins and their roles in the regulation of organelle transport. They have also developed precision imaging methods to resolve how large master-regulatory scaffolding proteins assemble multiple protein complexes locally on organelle surfaces, and coordinate the dynamics of membrane and cytoskeletal regulatory proteins during organelle biogenesis. Motivated by the need to visualize the complex sets of interactions among bio-macromolecules in protein complexes and molecular-cell pathways, the Diehl Laboratory has also developed a new class of programmable molecular imaging technologies that can expand the number of biomarkers that can be imaged simultaneously using either conventional or super-resolution optical microscopy. They are employing these technologies for comprehensive and spatially-delineated in situ analyses of protein network states within single cells and tissue sections with high resolution. Such capabilities are critical to numerous developmental cell studies as well as fundamental and clinical efforts to characterize the molecular signatures and pathologies of diseases. All of these advances are made possible by combining expertise in biomaterials engineering, molecular biology, optics and microscopy, hyperspectral imaging, single-molecule biophysics, and computational modeling.

     
    Teaching Areas
     Cellular Engineering, Biophysics, Molecular Imaging
     
    Selected Publications
     Refereed articles
     

    David S. Tsao, R. Tyler McLaughlin, Nicholaus Trenton, Satya K. Bellamkonda, Emily M. Mace, Jordan S. Orange, Volker Schweikhard, Michael R. Diehl "Live-cell delineation of multiple tethering modes by the scaffold IQGAP1 ." Journal of Biological ChemistrySubmitted

     
     

    Samson, Edward B; Tsao, David S; Zimak, Jan; McLaughlin, R Tyler; Trenton, Nicholaus J; Mace, Emily M; Orange, Jordan S; Schweikhard, Volker; Diehl, Michael R; "The coordinating role of IQGAP1 in the regulation of local, endosome-specific actin networks." Biology open, 6 (2017) : 785-799.

     
     

    Wang, Qian; Diehl, Michael R; Jana, Biman; Cheung, Margaret S; Kolomeisky, Anatoly B; Onuchic, José N; "Molecular origin of the weak susceptibility of kinesin velocity to loads and its relation to the collective behavior of kinesins." Proceedings of the National Academy of Sciences, 114 (2017) : E8611-E8617.

     
     

    E.B. Samson, J. Zimak, B. Long, A. Qutub, E. Mace, J.S. Orange, V. Schweikart, M.R. Diehl “IQGAP1 regulates the multiple specialized cytoskeletal networks in polarized epithelial cells“ – Journal of Cell Biology submitted (2016).

     
     

    Adam R. Wolfe, Bisrat G. Debeb, Lara Lacerda, Richard Larson, Arvind Bambhroliya, Xuelin Huang,Francois Bertucci, Pascal Finetti, Daniel Birnbaum, Steven Van Laere, Parmeswaran Diagaradjan, Brian Ruffell, Nicholaus J. Trenton, Khoi Chu, Walter Hittelman, Michael Diehl, Ilya Levental ,Naoto T. Ueno, Wendy A. Woodward. (2015) Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a. Breast Cancer Research and Treatment. 154, 495-508

     
     

    E. Kumar, D.S. Tsao, A. Radhakrishnan, M.R. Diehl “Building cells for quantitative, live-cell analyses of collective motor protein functions.” Methods in Enzymology 128: 69–82 (2015).

     
     

    T. McLaughlin, M.R. Diehl, A.B. Kolomeiski “Collective dynamics of cytoskeletal motor proteins’ Soft Matter 12(1):14-21. (2015)

     
     

     T. McLaughlin, M.R. Diehl, A.B. Kolomeiski “Frameworks for analyses of collective motor functions’ Softmatter invited and in preparation (2015)

     
     

    A. Rogers, P.E. Constantinou, D.K. Jamison, J.W. Driver, M.R. Diehl "Construction and analysis of elastically coupled multiple-motor systems." Methods in Enzymology, 520

     
     

    A.K. Efremov, A. Radhakrishan, D.S. Tsao, C.S. Bookwalter, K.M. Trybus, M.R. Diehl "Delineating cooperative responses of processive motors in living cells." Proceedings of the National Academy of Sciences, USA 111: E334-E4343 .

     
     

    D.S. Tsao, M.R. Diehl "Molecular motors: myosins move ahead of the pack." , 9: 9-10 .

     
     

    Eric Kumar, David Tsao, M. R. Diehl "Motor mutants bring wild-type motors to a halt stochastically." Biophysical Journal , 107: 279-281.

     
     

    A.K. Efremov, A. Radhakrishan, D. Tsao, C.S. Bookwalter, K.M. Trybus, M.R. Diehl “Delineating cooperative responses of processive motors in living cells” accepted to PNAS (2013)

     
     

    D.K. Jamison, J.D. Driver, M.R. Diehl “Structure-function analyses of single, multiple motor complexes” invited and in preparation for special issue in Methods in Enzymology (October 2013).

     
     

    D.S. Tsao, M.R. Diehl. “Molecular motors: myosins move ahead of the pack” Nature Nanotechnology 9, 9-10 (2014).

     
     

    K. Uppulary, J.W. Driver, M.R. Diehl, A.B. Kolomeisky “Analysis of cooperative responses of multiple kinesin motors to structural and chemical factors” Journal of Cellular and Molecular Bioengineering 6, 38-47 (2013). 

     
     A. R. Rogers, J. Driver, P.E. Constantinou, M.R. Diehl Collective transport of interacting kinesin-1 in the absence of applied loads, invited publication to appear in June issue of Physical Chemistry Chemical Physics.
     
     

    D.K. Jamison, A. Rogers, P.E. Constantinou, M.R. Diehl; Enhanced Force Production by Two Interacting Kinesin-1 Motors through the Coupling of Internal Strain Science  Submitted

     
     

    R. Schweller, N. Frankel, P. Constantinou, P. Narayan, M.R. Diehl: Design of DNA-Conjugated Polypeptide-based Capture Probes for the Anchoring of Proteins to DNA Matrices, Bioconjugate Chemistry 19, 2304-2307 (2008).

     
     Articles
     

    D.K Jamison, J. Driver, M.R. Diehl "Cooperative responses of multiple kinesins to variable and constant loads" Journal of Biological Chemistry 287, 3357-3365 (2012)

     
     

    D.Y. Duose, R.M. Schweller, J. Zamak, A. Rogers, W.N. Hittelman, M.R. Diehl "Configuring robust DNA strand displacement reactions for in situ molecular analyses" Nucleic Acids Research 40, 3289-3298 (2012)

     
     

    H. Lu, A.K. Yefremov, C.D. Bookwalter, E.B. Kremestsova, J.W. Driver, K. Trybus, M.R. Diehl "Cooperative dynamics of elastically-coupled myosinV motors" Journal of Biological Chemistry 287, 27253-27761 (2012)

     
     

    J. Zimak, R.S. Schweller, W.N. Hittelman, M.R. Diehl "Programming in situ immunofluorescence intensities through interchangeable reactions of dynamic DNA complexes" ChemBioChem, Dec 21;13(18):2722-8.

     
     

    K. Uppulary, A.K. Efremov, J.W. Driver, D.K. Jamison, M.R. Diehl, A.B. Kolomeisky "How the interplay between mechanical strain and non-mechanical interactions affect multiple kinesin dynamics" Journal of Physical Chemistry B 116, 8846-8855 (2012)

     
     

    K. Uppulary, J.W. Driver, M.R. Diehl, A.B. Kolomeisky “Analysis of cooperative responses of multiple kinesin motors to structural and chemical factors” Journal of Cellular and Molecular Bioengineering: Special issue on biomolecular motors and motor assemblies, 6, 38-47 (2013).

     
     

    M.R. Diehl “Templating a molecular tug-of-war” Science 338, 626-623 (2012)

     
     

    R.S. Schweller, J. Zimak, D.Y. Duose, W.N. Hittelman, M.R. Diehl. "Multiplexed in situ immunofluorescence via dynamic DNA complexes" Angewandte Chemie 51, 9292-9296 (2012)

     
     

    D.Y. Duose, R.M. Schweller, J. Zamak, A. Rogers, W.N. Hittelman, M.R. Diehl “Configuring robust DNA strand displacement reactions for in situ molecular analyses” Nucleic Acids Research, 40, 3289-3298 (2012).

     
     

    D.K Jamison, J. Driver, M.R. Diehl “Cooperative responses of multiple kinesins to variable and constant loads” – Journal of Biological Chemistry 287, 3357-3365 (2012).

     
     

    J.W. Driver, D.K. Jamison, A.R. Rogers, K. Uppulury, A.B. Kolomeisky,  M.R. Diehl “Productive cooperation among processive motors depends on their mechanochemical efficiencies” Biophysical Journal 101, 386 (2011)

     
     

    K.I. McConnell, R.M. Schweller, M.R. Diehl, J. Suh. “Live-cell microarray surface coatings supporting reverse transduction by adeno-associated viruses” BioTechniques 51, 255-258 (2011)

     
     

    D.K. Jamison, J.W. Driver, A.R. Rogers, P.E. Constantinou, M.R. Diehl “Two Kinesins Transport Cargo Primarily via the Action of One: Implications for Intracellular Transport,” Biophysical Journal 99, 2967-2977 (2010).

     
     

    D.W. Driver, A.R. Rogers, D.K. Jamison, R.K. Das., A.B. Kolomeisky, M.R. Diehl “Coupling between Motor Proteins Determines Dynamic Behaviors of Motor Protein Assemblies” Physical Chemistry Chemical Physics 12, 10398 (2010)

     
     

    D.Y. Duose, R.M. Schweller, W.N. Hittelman, M.R. Diehl “Multiplexed and Reiterative Fluorescent Labeling via DNA Circuitry” Bioconjugate Chemistry 21, 2327-2331 (2010).

     
     

    A. R. Rogers, J. Driver, P.E. Constantinou, M.R. Diehl "Negative Interference Dominates Collective Transport of Kinesin Motors in the Absence of Load" PCCP 11, 4882 (2009)

     
     

    P.E. Constantinou, M.R. Diehl "The Macromolecular Hierarchy of Intracellular Transport" Journal of Biomechanics - in press (2009)

     
     

    K. Zhang, M.R. Diehl, D.A. Tirrell "Artificial Polypeptide Scaffold for Protein Immobilization." J. Am. Chem. Soc., 127 (2005) : 10136.

     
     

    M.R. Diehl*, K. Zhang, H.J. Lee, D.A. Tirrell "Engineering Cooperativity in Biomotor-Protein Assemblies." Science, 311 (2006) : 1468.

     
     

    M.R. Diehl, D.W. Steuerman, H-R. Tseng, S.A. Vignon, A. Star, P.C. Celestre, J.F. Stoddart, J.R. Heath "Single-Walled Carbon Nanotube-Based Molecular Switch Tunnel Junctions." Chem. Phys. Chem., 4 (2003) : 1335.

     
     

    M.R. Diehl, J.-Y.Yu, J.R. Heath, G.A. Held, H. Doyle, S. Sun, C.B. Murray "Crystalline, Shape, and Surface Anisotropy in Two Crystal Morphologies of Superparamagnetic Cobalt Nanoparticles by Ferromagnetic Resonance." J. Phys. Chem. B., 105 (2001) : 7913.

     
     

    M.R. Diehl, S. Yaliraki, R. Beckman, M. Barahona, J.R. Heath "Self-Assembled, Deterministic Carbon Nanotube Wiring Networks." Angew. Chem. Int. Ed., 41 (2002) : 353.

     
     Conference papers
     

    Schweikhard, Volker; Samson, Edward; Tsao, David; McLaughlin, Tyler; Diehl, Michael; "Coordinating Role of IQGAP1 in the Regulation of Multivesicular Endosomal Compartment Dynamics." Biophysical Journal, 112 (2017) : 431a.

     
     

    Schweikhard, Volker; Samson, Edward; Tsao, David; McLaughlin, Tyler; Diehl, Michael; "Coordinating Role of IQGAP1 in the Regulation of Multivesicular Endosomal Compartment Dynamics." Biophysical Journal, 112 (2017) : 431a.

     
     

    Wang, Qian; Cheung, Margaret; Diehl, Michael; Onuchic, José; Jana, Biman; Kolomeisky, Anatoly; "Cooperativity of Kinesin Motor Proteins under External Loads." Biophysical Journal, 112 (2017) : 426a.

     
     

    Wang, Qian; Cheung, Margaret; Diehl, Michael; Onuchic, José; Jana, Biman; Kolomeisky, Anatoly; "Cooperativity of Kinesin Motor Proteins under External Loads." Biophysical Journal, 112 (2017) : 426a.

     
    Presentations
     Invited Talks
     

    "Department of Nanotechnology, Methodist Research Institute “Visualizing dynamic functions of signaling scaffolds (November 2017).." (November 2017)

     
     

    Biophysical Society Meeting, San Francisco, CA (March 2016): “Systems and synthetic approaches to understanding organelle dynamics”. 

     
     

     Department of Molecular Physiology and Biophysics, University of Vermont Medical School (September 2015): “Synthetic manipulation and analyses of cytoskeletal transport and structural regulatory proteins”.

     
     

     Center for Human Immunobiology – Texas Children’s Hospital. Houston TX (September 2015): “Systems and synthetic approaches to investigating cytoskeletal regulation”.

     
     

    Jan Zimak, David Tsao, Eric Kumar, Tyler McLaughlin and Michael R Diehl "Synthetic approaches to investigate intracellular transport and cytoskeletal regulatory systems" AICHE program in Synthetic Biology: Engineering and Design (SEED). Manhattan Beach, CA (2014.)

     
     

    M.R Diehl, D.S. Tsao (presenter), E. Kumar. “Synthetic tools for delineating multiple motor functions in living cells” Annual Biophysical Society Meeting, San Francisco, CA (2014).

     
     

    Gordon Research Conference: Muscle and Molecular Motors. Mount Snow, Vermont (July 2014) Session: Motors with Cargos, in Ensembles, and Emergent Behaviors. Tapping synthetic biology for systems-level analyses and control over collective transport processes in living cells”.

     
     

    ‘Multi-scale Motility of Molecular Motors’ symposium, Max Plank Institute of Colloids and Interfaces. Potsdam, Germany (September 2013): ‘Synthetic approaches to delineating multiple motor functions in living cells”.

     
     

    Annual CTBS symposium, Innovations in Cellular Systems Biology: Modeling and Imaging session; Houston, TX (November 2012): “In situ proteomic analyses via multiplexed and reiterative imaging approaches”.

     
     

    NSF Center for Computational Physics, Rice University, Houston, Texas (September 2013) “Macromolecular Systems Biology”

     
     

    FASEB ‘Molecular Bioengineering’ symposium; Boston, MA (April 2013): “Single molecule approaches to dissecting network multiple protein functions”.

     
     

    "A. Radhakrishnan (presenter), Artem Efremov, J.C. Meijas, M.R Diehl "Inducible control of kinesin transport in living cells" Horizons in Molecular Biology International Research Symposioum, Goettingen, Germany (2012)." (2012)

     
     

    "Biophysical Society Meeting, Special Session: Cargo transport by multiple motors; San Diego, CA (February 2012): "Collective dynamics of multiple microtubule motors: connecting in vitro observations to in vivo functions"." (February 2012)

     
     

    "Center for Biomolecular Structure and Function, MD Anderson Cancer Center (February 2012): "Macromolecular systems biology"." (February 2012)

     
     

    "Department of Systems Biology, MD Anderson Cancer Center (April 2012): "Macromolecular approaches to systems biology"." (April 2012)

     
     

    "J. Zimak (presenter), R.M. Schweller, D.Y. Duose, M.R. Diehl ‘Discretized antibody signal modulation using branched DNA for fluorescence imaging" Southern Biomedical Engineering Conference, Houston, TX (May 2012)." (May 2012)

     
     

    "J. Zimak (presenter), R.M. Schweller, D.Y. Duose, W.N. Hittelman, M.R. Diehl "Discretized antibody signal modulation using branched DNA for fluorescence imaging" Biomedical Engineering Society Meeting, Atlanta, GA (October 2012)." (October 2012)

     
     

    "M.R. Diehl (presenter) ‘MEMS, NEMS and molecular machines – a tutorial' NANOCOURSE: Design and Implementation for First-in-human oncology trials, MD Anderson Cancer Center (July 2012)." (July 2012)

     
     

    "Multiplexed Imaging conference, MD Anderson Cancer Center (December 2012): "Multiplexed in situ proteomics via dynamic DNA technologies"." (December 2012)

     
     

    "NIH / NCI ‘Innovative Molecular Technologies’ Symposium; Houston TX (November 2012): "Highly-multiplexed, spatially-delineated molecular imaging in cancer"." (November 2012)

     
     

    "R.M. Schweller (presenter), J. Zimak, D.Y. Duose, W.N. Hittelman, M.R. Diehl "High-content molecular imaging and analyses through reactive DNA probe complexes" Southern Biomedical Engineering Conference, Houston, TX (May 2012)." (May 2012)

     
     

    "USACM meeting on Multiscale Methods and Validation in Medicine and Biology: Biomechanics and Mechanobiology; San Francisco, CA (February 2012): "Predicting cooperative dynamics of motor proteins from single-motor measurements"." (February 2012)

     
     

    M.R. Diehl “Macromolecular Systems Bioengineering”.  Department of Bioengineering, University of Washington (January 2011)

     
     

    M.R. Diehl “Principles Governing Cooperation among Processive Molecular Motors” Telluride Science Research Center Workshop: Rise of the Molecular Machines. Telluride, CO (August 2011)

     
     

    M.R. Diehl “Systems and Synthetic Biology Approaches to Investigating Molecular Pathways Governing Intracellular Transport Regulation” Department of Biomedical Engineering, Texas A&M University (March 2011)

     
     

    M.R. Diehl “The Influence of a Processive Motor's Mechanochemical Efficiency on Collective Motor Function” Gordon Research Conference: Muscle and Molecular Motors. Colby Sawyer College, New London, New Hampshire (July 2011)

     
     

    M.R. Diehl “Macromolecular Systems Bioengineering: Structure and Dynamics” Department of Biomedical Engineering, Ohio State University, (April 2010).

     
     

    M.R. Diehl “Synthetic and Biophysical Strategies to Investigate Cooperativity Among Multiple, Interacting, Kinesin-1 Motors” Los Alamos National Labs Conference: Thermodynamics and Kinetics of Molecular Motors, Santa Fe, (May 2010).

     
     

    D.K. Jamison, J.D. Driver, M.R. Diehl “Collective behaviors of multiple interacting kinesin motors: Can kinesin number regulate intracellular transport?” MBI workshop: Transport in the Cell, Columbus, Ohio (April 2010).

     
     

    M.R. Diehl, M.R. “Macromolecular Systems Bioengineering: Structure and Dynamics” Department of Anatomy & Structural Biology, Albert Einstein School of Medicine (January 2010)

     
     

    Diehl, M.R.; Jameson, D.K., Zimmerman, M., Driver, J.D., Rogers, A.R. “Multiple Interacting Kinesin-1 Motors Cooperate Negatively” Biophysical Society Meeting, San Fansico, CA (March 2010).

     
     

    M.R. Diehl “Reiterative Fluorescent Labeling via DNA-Circuitry” NSF: DNA-Nanotechnology Workshop, Oxnard CA (January 2010).

     
     

    M.R. Diehl “The role of multiple motor dynamics in intracellular transport” Department of Molecular Physiology and Biophysics, University of Vermont Medical School (November 2010).

     
     

    M.R. Diehl, Kenneth Jameson, Arthur Rogers. "Collective Stepping Mechanics and Force Production of Two Coupled Kinesin Motors" Motility Subgroup Symposium: National Biophysical Society Meeting Boston, MA (March 2009)

     
     

    M.R. Diehl "Collective Transport of Kinesin-1 Motors" Department of Physics, University of Texas, Austin (September 2009)

     
     

    M.R. Diehl, "Cooperativity in Systems of Two Elastically-Coupled Kinesin Molecules is Force Dependent" Single Molecule Biophysics meeting at the Aspen Center for Physics in Aspen, CO (January 2009)

     
     

    M.R. Diehl "Emergent Properties of Macromolecular Systems Containing Multiple Molecular Motors"   Emergence in Chemical Systems 2.0 conference; Anchorage, AK (June 2009)

     
     

    M.R. Diehl "Macromolecular Systems Bioengineering" Department of Bioengineering, University of California, Berkeley (February 2009)

     
     

    M.R. Diehl "Multiplexed, Reiterative Biomarker Imaging Via DNA Circuit Technologies" Emerging Technologies for Systems Biology Symposium. M.D. Anderson Cancer Center, Houston, TX (August 2009)

     
     

    M.R. Diehl "The Collective Dynamics of Interacting Motor Molecules" Department of Physics, Wake Forest University (November 2009)

     
     Michael R. Diehl A Macromolecular-Systems Approach to Investigating the Collective Dynamics of Interacting Motor Proteins Department of Biochemistry and Cell Biology Rice University August 2008
     
     Michael R. Diehl Arthur Rogers Kenneth Jameson Biosynthetic and Single-Molecule Approaches to Study Multi-motor Transport Recent Advances in Biophysical Chemistry of Transport by Biomolecular Motors and Machines: National ACS Meeting Philadelphia PA August 2008
     
     Biomedical Engineering Society Rita Schafer Planary Lecture, Los Angeles CA. “Engineering Cooperativity in Motor Protein Assemblies”
     
     

    "Investigating multi-protein dynamics with single-molecule sensitivity." Baylor Univ. Department of Chemistry and Biochemistry, Waco TX. (Dec 1, 2006)

     
     Lectures
     

    Esther J. Lee (presenter), Jan Zimak, Michael R. Diehl, Jeffrey J. Tabor, Antonios G. Mikos “An Optogenetics-Based Platform for Bone Morphogenetic Protein-2 Delivery” TERMIS, Houston TX (2015).

     
     

     Papiya Sinha (presenter), David Tsao, Emily M. Mace, Anatoly Kolomeisky, Michael Diehl and Jordan S. Orange. “Coordinated interrelated cytoskeletal functions regulate extensive physiologic NK cell lytic granule motility after arrival at the immunological synapse.” NK2015 – 15th Meeting of the Society for Natural Immunity. Montebello, Quebec (Canada); May (2015).

     
     

    V. Schweikhard, E.B. Samson, J. Zimak, M.R. Diehl Local and non‐local roles for the scaffold protein IQGAP1 in the regulation of epithelial cell junctions. (December 2015)

     
     

    Nick Trenton (presenter), Jan Zimak, Khoi Cho, Walter N. Hittelman, Wendy Woodward, Michael R. Diehl “Spatially multiplexed multicellular analyses of cancer-immune cell interactions in inflammatory breast cancer” Bioengineering Society Meeting, Tampa FL (2015).

     
     

    M.R. Diehl “Molecular Profiling with DNA-Circuitry Probes” NSF: Molecular Programming Workshop, Oxnard CA (June 2011)

     
     Other
     

    NIH Grant Panelist: NCI IMAT study section [ZCA1 SRLB(Q)M1 panel] (March 2014)

     
     Kenneth Jameson, Arthur Rogers, and Michael R. Diehl Collective Motility and Force-Generation of Exactly Two Coupled Kinesin-1 Motors National American Society of Cell Biology Meeting San Francisco, CA December 2008
     
     Arthur Rogers Kenneth Jamison, Pamela Constantinou, Jonathan Driver, and Michael R. Diehl Single- Molecule Approaches to Investigate Collective Motor Transport Gordon Research Conference: Muscle and Molecular Motors Colby-Sawyer College, New London, NH June 2008
     
     

    "Investigating Integrated Multi-Protein Dynamics with Single-Molecule Sensitivity, Designed Macromolecular Assemblies for Biomedical Applications: National ACS Meeting Chicago, IL (March 2007). ." With Michael R. Diehl, Pamela Constantinou, Dzifa Douse, Arthur Rogers, and Kenneth Jamison

     
     

    "Engineering cooperativity in biomotor-protein assemblies." Gordon Research Conference, New London, NH. (June, 2006)

     
     

    "Self-Assembling Multi-Component Assemblies of Motor Proteins." Biophysical Society, Asilomar, CA. (October 2006) With D. Douse, P Constantinou

     
     Posters
     

    " V. Schweikhard , E.B. Samson, D. Tsao, T. McLaughlin, Multiplexed imaging of signaling scaffolds. Quantitative Bioimaging (QBI) conference Jan. 5 – 7. (College Station, TX)." (January 2017)

     
     

    "Q Wang, M Diehl, B Jana, M Cheung, J Onuchic, A Kolomeisky "Inter-head Tension of Cytoplasmic Dynein Regulates the Coordination between Two Heads" Bulletin of the American Physical Society Meeting. (Los Angeles, CA)." (March 2018)

     
     

    A. Radhakrishnan (presenter), Artem Efremov, J.C. Meijas, M.R Diehl “Synthetic approaches to dissecting intracellular transport mechanisms in living cells” Annual Biophysical Society Meeting, Philadelphia, PA (2013).

     
     Workshops
     

     Jan Zimak (presenter), E. Sampson, V. Schweikard, David Tsao, Tyler McLaughlin and Michael R Diehl "Synthetic approaches to dissect the multiple cytoskeletal regulatory functions of IQGAP1" Mammalian Synthetic Biology Workshop 2.0. Boston, MA (2015.)

     
    Editorial Positions
     Other, Biomech. and Modeling in Mechanobiology. (2013 - 2014)

     Other, Journal of Physics: Condensed Matter. ‘Physics of protein motility / Motor proteins’ (December 2012). (2012 - 2012)

     Other, Advance Functional Materials. (2013 - 2013)

     Other, Advance Functional Materials. (2013 - 2014)

     Other, Physical Biology. (2013 - 2014)

     Other, Nature Nanotechnology. (2013 - 2014)

     Other, ChemPhysChem. (2013 - 2014)

     Other, Neurosurgery. (2013 - 2014)

     Other, Cell Motility and the Cytoskeleton. (2013 - 2014)

     Other, Nature. (2013 - 2014)

     Other, European Journal of Physics. (2013 - 2014)

     Other, PLoS ONE. (2013 - 2014)

     Other, Biomacromolecules. (2013 - 2014)

     Other, Cellular and Molecular Bioengineering. (2013 - 2014)

     Other, Biophysical Journal. (2013 - 2014)

     Other, Advanced Materials. (2013 - 2015)

     Other, MRS Research Journal. (2013 - 2014)

     Other, Nature Reviews. (2013 - 2014)

     Other, PNAS. (2013 - 2014)

     Other, Science. (2013 - 2014)

     Other, Nanoletters. (2013 - 2014)

    Supervised Theses & Dissertations
     Athanasios Dousis, Graduate Student. (Thesis Committee Member)

     Konstantin Tsvaygboym. (Thesis Committee Member)

     Brian Kirk. (Thesis Committee Member)

     Ivan Birukou, BCB. (Thesis Committee Member)

     Cariss Smith, Chemistry. (Thesis Committee Member)

     Konstantin Tsvaygboym, Bioengineering. (Thesis Committee Member)

     Brian Kirk, Bioengineering. (Thesis Committee Member)

     Ting Sun, ECE. (Thesis Committee Member)

     Megan Guelker, BCB. (Thesis Committee Member)

     Athanasios Dousis, Bioengineering. (Thesis Committee Member)

    Awards, Prizes, & Fellowships
     NAFKI Keck Futures Award,

     IBB Medical Innovation Award,

     Garden State Scholar,

     Edward J. Bloustein Distinguished Scholar, The College of New Jersey

     Dissertation Award , Physical Chemistry, University of California at Los Angeles

     Beckman Senior Research Fellowship, California Institute of Technology

     Neshamkin Award in Chemistry,

     Hamill Research Innovation Award,

     NSF CAREER Award,

     HSEMB Outstanding Young Scientist Award,

     W.M. Keck Foundation, Research Excellence Award,

     Rita Schaffer Young Investigator Award, The Biomedical Engineering Society

     HSEMB Outstanding Young Scientist Award,

     Welch Foundation Research Grant, (2006-2012)

     NIH R01 , NIGMS (2010-2015)

     CAREER Award, NSF (2007 - 2012)

     Army Medical Research and Material Command, USARMMC (2009-2011)

     NIH R21 , NCI (2010-2013)

     Research Excellence Award, W.M. Keck Foundation (2008)

     Rita Schaffer Young Investigator Award, The Biomedical Engineering Society, (2007)

     Hamill Research Innovation Award, (2006-2007)

    Positions Held
     Grant reviewer for Research Corporation for Science Advancement, Cottrell College Science Award. (2014 - 2014)

     Ad hoc NSF Grant reviewer, Division of Molecular and Cellular Biosciences . (2014 - 2014)

     Ad hoc NSF Grant reviewer, Molecular Biophysics . (2014 - 2015)

     Member, American Society for Biochemistry and Molecular Biology. (2014 - 2014)

     Member, Biophysical Society. (2014 - 2014)

     Member, American Chemical Society. (2014 - 2014)

     Member, Biomedical Engineering Society. (2014 - 2014)