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Scholarly Interest Report
         
Yigong Shi
Adjunct Professor
Adjunct Professor of Chemistry
 
e-mail:Yigong.Shi@rice.edu
 
  • B.S. Biology and Mathematics (1989) Tsinghua University, Beijing, China
  • Ph.D. Biophysics and Biophysical Chemistry (1995) Johns Hopkins University School of Medicine, Baltimore, Maryland
 
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Department Affiliations
 
  • Department of Chemistry
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    Websites
     Yigong Shi's Research Group Website
     

    2013 Research Statemetn

     

    Research in our laboratory at Tsinghua University is primarily focused on the elucidation of molecular mechanisms of programmed cell death (apoptosis).  Towards this goal, we have determined over 20 crystal structures of important proteins and protein complexes that govern the initiation and execution of apoptosis in mammals, Drosophila melanogaster, and Caenorhabditis elegans.  We are also expanding our research effort into other functional biological pathways.