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Scholarly Interest Report
         
Joseph B. Hughes
Adjunct Professor
Adjunct Professor of Civil and Environmental Engineering
 
e-mail:hughes@rice.edu
 
  • B.A. Chemistry (1987) Cornell College, Mount Vernon, IA
  • M.S. Civil and Environmental Engineering (1989) University of Iowa, Iowa City, IA
  • Ph.D. Civil and Environmental Engineering (1992) The University of Iowa, Iowa City, IA
 
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Websites
 More Info
 
Research Areas
 Environmental Biotechnology
 
Research Statement
 Dr. Hughes' reserach specializes in the area
of Environmental Biotechnology, in particular
determining how the novel metabolic
capabilities of living organisms can be
harnessed to improve the environment in
which we live. Recent research projects
under Dr. Hughes' direction have focused on
how bacteria and plants metabolize
hazardous organic pollutants. In particular,
chlorinated solvents, nitroaromatic
compounds and polynuclear aromatic
hydrocarbons. The current focus of these
studies centers on interactions between
contaminant phase distribution (i.e.,
non-aqueous, sorbed, soluble) and metabolic
rates, along with the analysis of product
formation and distribution.
 
Selected Publications
 Books
 

Spain, J., H. Knackmuss, and J.B. Hughes, Editors "Metabolism of Nitroaromatics and Explosive Compounds." 

 
 Other
 

Ahmad, F. and J.B. Hughes "The Reactivity of Partially Reduced Metabolites of 2,4,6-Trinitrotoluene (TNT): 1. Product Distribution and Binding in a Cell-Free Bioreduction System." Environmental Science and Technology (Submitted October 2001)

 
 

Ahmad, F. and J.B. Hughes "The Reactivity of Partially Reduced Metabolites of 2,4,6-Trinitrotoluene (TNT): 2, An Evaluation of the Reactivity of Arylhydroxylamines and Nitrosoarenes Towards Humic Acids." Environmental Science and Technology (Submitted, October 2001)

 
 

Bhadra, R., D.G. Wayment, R.K. Williams, S.N. Barman, M.B. Stone, J.B. Hughes, and J.V. Shanks "Studies on Plant-Mediated Fate of the Explosives RDX andf HMX." Chemosphere, 44 (2001) : 1259-1264.

 
 

Cope, N. and J.B. Hughes "Biologically-Enhanced Removal of PCE and NAPL Source Zones." Environmental Science and Technology, (35) (2001) : 2014-2021.

 
 

Schnoor, J. and J.B. Hughes "Phytoremediation." Environmental Restoration (2001 in press)

 
 

Ward, C.H., J. Spain and J.B. Hughes "In-situ Treatment Processes." Environmental Restoration (in press 2001)

 
 

Zhang, C., R.C. Daprato, S.F. Nishino, J.C. Spain and J.B. Hughes "Remediation of Dinitrotoluene Contaminated Soils from Former Army Ammunition plants: Soil Washing Efficiency and Effective Process Monitoring in Bioslurry Reactors." Journal of Hazardous Materials, B87 (2001) : 139-154.

 
 

Zheng, D., C.S. Carr. amd J.B. Hughes "Influence of Hydraulic Retention Time on Extent of PCE Dechlorination and Preliminary Characterization of the Enrichment Culture." Bioremediation Journal, (5) (2001) : 159-168.

 
 

Ahmad, F. and J.B. Hughes "Anaerobic Transformation of TNT byClostridia." Metabolism of Nitroaromatics and Explosive Compounds (2000) : 185-212.

 
 

Carr, C.S., S. Garg, and J.B. Hughes "Effect of Dechlorination on the Longevity and Composition of NAPL Sources under Equilibrium Dissolution Conditions." Environmental Science and Technology, 34 (2000) : 1088-1094.

 
 

Huang, S., P.A. Lindahl, C. Wang, G.N. Benett, F.B. Rudolph, and J.B. Hughes "2,4,6-Trinitrotoluene (TNT) Reduction by Carbon Monoxide Deydrogenase from Clostridium thermoaceticum." Applied and Environmental Microbiology, 66 (2000) : 1474-1478.

 
 

Hughes, Joseph B., C. Nelson Neale, and C.H. Ward "Bioremediation." Encyclopedia of Microbiology, 1 (2000) : 587-610.

 
 

Neale, C.N., J.B. Hughes and C.H. Ward "Impacts of Unsaturated Zone Properties on Oxygen Transport and Aquifer Reaeration." Groundwater, 38(5) (September-October 2000) : 784-794.

 
 

Neale, Nelson, Anthony Holder, Herb Ward and Joseph Hughes "Ground Water Reaeration Effects on Hydrocarbon Plumes: A Modeling Approach ." ASCE Journal of Environmental Engineering (Accepted)

 
 

Padda, R.S., C.Y. Wang, J.B. Hughes, and G.N. Bennett "Mutagenicity of Trinitrotoluene and its Metabolites Formed During Anaerobic Degradation by Clostridium acetobutylicumATCC 824." Environmental Toxicology and Chemistry, 19 (accepted) : 2871-2875.

 
 

Tadros, M.G., A. Crawford, A. Mateo-Sullivan, C. Zhang, and J.B. Hughes "Toxic Effects of Hydroxylamino Intermediates from Microbial Transformation of Trinitrotoluene and Dinitrotoluenes on Algae Selenastrum capricornutum." Bulletin of Environmental Contamination and Toxicology, 64 (2000) : 579-585.

 
 

Wang, C.Y., D. Zheng, and J.B. Hughes "Stability of Hydroxylamino and Amino Intermediates from Reduction of 2,4, 6-Trinitrotoluene, 2,4-Dinitrotoluene and 2,6-Dinitrotoluene." Biotechnology Letters, 22 (2000) : 15-19.

 
 

Zhang, C., J.B. Hughes, S.F. Nishino, and J.C. Spain "Slurry-Phase Biological Treatment of 2,4-Dinitrotoluene and 2,6-Dinitrotoluene: Role of Bioaugmentation and Effects of High Dinitrotoluene Concentrations." Environmental Science and Technology, 34 (2000) : 2810-2816.

 
 

Ahmad, F. and J.B. Hughes "Metabolism of Nitroaromatic Compounds by Clostridia." Nitroaromatic Metabolism (September 1999)

 
 

Beckles, D.M., S. Friedfeld, A.T. Kan, M.B. Tomson, and J.B. Hughes "Bioavailability of Desorption Resistant Naphthalene." Environmental Toxicology and Chemistry (August 1999)

 
 

Bhadra, R., D.G. Wayment, J.B. Hughes, and J.V. Shanks "Confirmation of Conjugation Processes During TNT Metabolism by Axenic Plant Roots." Environmental Science and Technology, 33 (1999) : 446-452.

 
 

Bhadra, R., D.G. Wayment, J.B. Hughes, and J.V. Shanks "Conjugate Formation During the Metabolism of 2,4,6-Trinitrotoluene in Plant Roots." Phytoremediation and Innovation Strategies for Specialized Remedial Applications (1999) : 121-126.

 
 

Bhadra, R., R.J. Spanggord, D.G. Wayment, J.B. Hughes and J.V. Shanks "Characterization of Oxidation Products of TNT Metabolism in Aquatic Phytoremediation Systems of Myriophyllum aquaticum." Environmental Science and Technology, 33 (1999) : 3354-3361.

 
 

Carr, C.S. and J.B. Hughes "Response to Comment: Enrichment of High Rate PCE Dechlorination and Comparative Study of Lactate, Methanol, and Hydrogen as Electron Donors to Sustain Activity." Environmental Science and Technology, 33 (1999) : 2683-2684.

 
 

Ferone, W.A., S.S. Koenigsbert, and J.B. Hughes "Chemical Dynamics Model for CAH Remediation with Polylactate Esters." Engineering Approaches for In Situ Bioremediation of Chlorianted Solvent Contamination (1999) : 287-292.

 
 

Fisher, R.T., C.J. Newell, P.E. Hass, and J.B. Hughes "Treatability Studies of Hydrogen-Enhanced Bioremediation of Chlorinated Solvent-Impacted Media." Engineering Approaches for In Situ Bioremediation of Chlorinated Solvent Contamination (1999) : 185-189.

 
 

Gerlach, R., C. Zhang, M. Steioff, and J.B. Hughes "Hydrophobic Electron Donors for the Reduction of Nitroaromatics in Anaerobic Sediments." Journal of Contaminant Hydrology, 36 (1999) : 91-104.

 
 

Holder, A.W., P.B. Bedient, and J.B. Hughes "Modeling the Impact of Oxygen Reaeration on Natural Attenuation." Bioremediation Journal, 3 (1999) : 137-149.

 
 

Hughes, J.B., C. Wang, and C. Zhang "Anaerobic Transformation of 2,4- and 2,6- Dinitrotoluenes by Clostridium acetobutylicum : A Pathway Through Dihydroxylamino-Intermediates." Environmental Science and Technology, 33 (1999) : 1065-1070.

 
 

Hughes, Joseph B. "Fate Processes." Groundwater Contamination: Transport and Remediation, 3rd edition (1999) : 203-236.

 
 

Reible, D., R. Chaney, and J.B. Hughes "Bioavailability." Environmental Availability in Soils: of Chlorinated Organics, Explosives, and Heavy Metals (1999)

 
 

Wayment, D.G., R. Bhadra, J. Lauritzen, J.B. Hughes, and J.V. Shanks "A Transient Study of Conjugate Formation During TNT Metabolism by Axenic Plant Roots." Journal of Phytoremediation, 1 (1999) : 227-239.

 
 

Beckles, D.M., C.H. Ward and J.B. Hughes "The Effect of Mixtures of PAHs and Sediments on Fluoranthene Biodegradation Patterns." Environmental Toxicology and Chemistry, 17 (1998) : 1246-1251.

 
 

Bhadra, R., D.G. Wayment, J.B. Hughes and J.V. Shanks "Biochemical Pathways of 2,4,6-Trinitrotoluene Abatement by Phytoremediation." AIChE Symposium Series, Topical Conference on Pollution Prevention and Environmental Reduction (To appear 1998)

 
 

Carr, C.S. and J.B. Hughes "Enrichment of High Rate PCE Dechlorination and Comparative Study of Lactate, Methanol, and Hydrogen as Electron Donors to Sustain Activity." Environmental Science and Technology, 32 (1998) : 1817-1824.

 
 

Holder, A.W., P.B. Bedient and J.B. Hughes "TCE and 1,2-DCE Biotransformation Inside a Biologically Active Zone." Natural Attenuation of Chlorinated Recalcitrant Compounds, 3 (1998) : 219-224.

 
 

Huang S., P.A. Lindahl, C. Wang, G.N. Bennett, F.B. Rudolph and J.B. Hughes "2,4,6-Trinitrotoluene (TNT) Reduction by Carbon Monoxide Deydrogenase from Clostridium thermoaceticum: Product Identification, Kinetic Characterization, and Inhibitor Study." Biochemistry (Submitted 1998 September)

 
 

Hughes, J.B., C. Wang and C. Zhang "Anaerobic Transformation of 2,4- and 2,6-Dinitrotoluenes by Clostridium acetobutylicum: A Pathway Through Dihydroxylamino-Intermediates." Environmental Science and Technology (Submitted 1998 September)

 
 

Hughes, J.B., C. Wang, K. Yesland, A. Richardson, R. Bhadra, G. Bennett and F. Rudolph "Bamberger Rearrangement During TNT-Metabolism by Clostridium acetobutylicum." Environmental Science and Technology, 32 (1998) : 494-500.

 
 

Hughes, J.B., C. Wang, R. Bhadra, A. Richardson, G. Bennett and F. Rudolph "Reduction of 2,4,6-Trinitrotoluene by Clostridium acetobutylicum through Hydroxylamino-Nitrotoluene Intermediates." Environmental Toxicology and Chemistry, 17 (1998) : 343-348.

 
 

Jee, V., D. Beckles, C.H. Ward and J.B. Hughes "Bioremediation of Phenathrene-Contaminated Estuarine Sediments." Water Research, 32 (1998) : 1231-1239.

 
 

Newell, C.J., J.B. Hughes, R.T. Fisher and P.E. Haas "Subsurface Hydrogen Addition for the In Situ Bioremediation of Chlorinated Solvents." Designing and Applying Treatment Technologies, 6 (1998) : 47-52.

 
 

Pucik, L.E. and J.B. Hughes "Fate of TNT and TNT-Transformation Products in Aerobic Mixed Cultures." Bioremediation Journal, 2 (1998) : 57-67.

 
 

Wang, C. and J.B. Hughes "Derivatization and Separation of 2,4,6-Trinitrotoluene Metabolic Products." Biotechnology Techniques, 12 (November 1998) : 839-842.

 
Presentations
 Other
 

"Biologically Enhanced DNAPL Dissolution: Role of NAPL Composition and Observed Contaminant Flux Rates, In Situ and On-Site Bioremediation." 6th International Symposium, San Diego, CA. (June 2001)

 
 

"DNAPL Source-Zone Bioremediation." NATO Advanced Study Institute Program on Innovative Approaches to the On-Site Assessment and Remediation of Contaminated Sites, Prague, Czech Republic. (May 2001)

 
 

"Earth Systems Engineering: What does it Mean?." Department of Civil, Environmental and Architectural Engineering, University of Colorado at Boulder, Boulder, CO. (May 2001)

 
 

"Engineering and the Environment." Department of Mechanical Engineering and Materials Science, Rice University, Houston, TX. (January 2001)

 
 

"Engineering and the Environment." Rice University's Women's Alumni Society, Houston, TX. (January 2001)

 
 

"Enhanced Bioremediaton of DNAPL Source Zones." Session Chair, 6th International Symposium, San Diego, CA. (June 2001)

 
 

"Explosives Compound Transformation." NATO Advanced Study Institute Program on Innovative Approaches to the On-Site Assessment and Remediation of Contaminated Sites, Prague, Czech Republic. (May 2001)

 
 

"Role of Reduction Intermediates in TNT Metabolism." Biofilm Engineering Research Center, Montana State University, Bozeman, MT. (October 2001)

 
 

"The Effect of Dechlorinating Bacteria on PCE-Containing NAPL." In-Situ and On-site Bioremediation, 6th International Symposium, San Diego, CA. (June 2001)

 
 

"Twelve Billion People: What are we Thinking About?." Address to the George R. Brown School of Engineering, Rice University, Houston, TX. (September 2001)

 
 

"Twelve Billion People: What are we Thinking about?." National Academy of Engineering and Alexander Van Humbolt Foundation 4th Annual German-American Frontiers of Engineering Symposium, Essen, Germany. (October 2001)

 
 

"Bioremediation of DNAPL Source Zones: Laboratory Confirmation and Field Evidence." Department of Civil and Environmental Engineering, Pennsylvania State University, State College, Pennsylvania. (October, 2000)

 
 

"Living on the Edge: Can we share a few hundred billion dollars." University of Iowa, Biocatalysis and Bioprocessing Distinguished Alumnus Address, Iowa City, Iowa. (November 2000)

 
 

"Metabolism of Nitroaromatics: What Happens when TNT Disappears." Hazardous Substance Research Centers Research Symposium, Pacific Grove, CA. (July 2000)

 
 

"Monitored Natural Attenuation." Johnson and Johnson International Environmental Symposia, San Juan, Puerto Rico. (April 2000)

 
 

"Ability of Dechlorination to Influence DNAPL Dissolution Rates." In Situ and On-Site Bioremediation, 5th International Symposium, San Diego, CA. (April 1999)

 
 

"Bioavailability of Desorption Resistant PAH's." Conference on Hazardous Waste Research: Gateways to Environmental Solutions, St. Louis, MO. (May 1999)

 
 

"Bioavailability of Irreversibly Sorbed PAHs in Slurry Reactors'." In Situ and On-Site Bioremediation, 5th International Sympsoium, San Diego, CA. (April 1999)

 
 

"Bioslurry Reactors." Session Chair, In Situ and On-Site Bioremediaton, 5th International Symposium, San Diego, CA. (April 1999)

 
 

"Hydroxylamine Formation and Fate During Anaerobic Metabolism of Nitroaromatic Explosives." Air Force Research Laboratory, Tyndall Air Force Base, FL. (February 1999)

 
 

"Hydroxylamine Formation and Fate During Anaerobic Metabolism of Nitroaromatic Explosives." Swiss Federal Institute for Science and Technology, Dubendorf, Switzerland. (March, 1999)

 
 

"Impact of Plants on the Fate of Explosives." Los Alamos National Laboratory, Los Alamos, NM. (January 1999)

 
 

"Metabolism of Nitroaromatic Metabolism by Clostridia." 2nd International Conference on Nitroaromatic Metabolism, Leesburg, VA. (September, 1999)

 
 

"Oxygen Flux Through Various Soils and its Impact on Biodegradation." In Situ and On-Site Bioremediation, 5th International Symposium, San Diego, CA. (April 1999)

 
 

"Reduction of Nitroaromatic Explosives by Clostridium acetobutylicum." In Situ and On-Site Bioremediation, 5th International Symposium, San Diego, CA. (April 1999)

 
 

"Electron Donor Delivery and In Situ Dechlorination." SERDP Partners in Environmental Technology 98 Symposium, Washington, D.C.. (December 1998)

 
 

"Integration of Natural Attenuation with Site Groundwater Management." Golder Natural Attenuation Seminar, San Francisco, CA. (November 1998)

 
Editorial Positions
 Member of the Editorial Board, Journal of Phytoremediation. (1999 - 1999)

 Member of the Editorial Board, Enzyme and Microbial Technology. (1999 - 1999)

Awards, Prizes, & Fellowships
 Member, National Research Council Committee on Bioavailability of Contaminants in Soils and Sediments (2001)

 Member, U.S. Environmental Protection Agency Committee on Monitored Natural Attenuation (2001)

 Member, Association of Environmental Engineering Professors (2001)

 Member, U.S. Department of Defense Strategic Environmental Research and Development Program (SERDP) Technical Advisory Committee (2001)

 Member, American Chemical Society (2001)

 American Chemical Society, (2000)

 U.S. Environmental Protection Agency, Committee on Monitored Natural Attenuation, (2000)

 U.S. Department of Defense Strategic Environmental Research and Development Program (SERDP) Technical Advisory Committee, (2000)

 National Research Council, Committee on the Bioavailability of Contaminants in Soils and Sediments, (2000)

 Association of Environmental Engineering Professors, (2000)

 American Chemical Society, (1999)

 Association of Environmental Engineering Professors, (1999)