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Scholarly Interest Report
         
Dennis Dean Cox
Professor
Professor of Statistics
 
e-mail:dcox@rice.edu
 
  • B.A. Mathematics (1972) University of Colorado
  • M.S. Mathematics (1976) University of Denver
  • Ph.D. Mathematics (1980) University of Washington
 
Primary Department
   Department of Statistics
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Department Affiliations
 
  • Ken Kennedy Institute for Information Technology
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    Other Affiliations
     
  • MD Anderson
  •  
    Websites
     Dr. Cox's webpage
     Dr. Cox's Web Page
     
    Research Areas
     Functional Data Analysis, Data Mining, Computational Statistics, Nonparametric Function Estimation, Spatial Statistics, Time Series Analysis, Monte Carlo Methods, Environmetrics, Bayesian Methods, Applied Statistics, Theoretical Statistics and Probability Theory
     
    Selected Publications
     Abstracts
     

    Zhu, H. and Cox, D. "A Functional Generalized Linear Model with Curve Selection in Cervical Pre-cancer Diagnosis Using Fluorescence Spectroscopy."  (2008)

     
     Refereed articles
     

    Woroszylo C, Cox DD "Constructive Approaches to Limit Approximations in Biochemical Reaction Networks." Mathematical SciencesSubmitted

     
     

    Yang JJ, Cox DD, Lee JS, Ren P, Choi T "Efficient Bayesian hierarchical functional data analysis with basis function approximations using Gaussian-Wishart processes." BiometricsSubmitted

     
     

    Zhu HX, Morris JS, Wei F, Cox DD "Multivariate Functional Response Regression, with Application to Fluorescence Spectroscopy in a Cervical Pre-Cancer Study." Computational Statistics and Data AnalysisSubmitted

     
     

    Wang L, Lee JS, Lane P, Atkinson EN, Zuluaga A, Follen M, MacAulay C, Cox DD "A statistical model for removing inter-device differences in spectroscopy." Optics Express (2014) In Press

     
     

    Lee JS, Follen M, Cox DD "Adaptively truncated Hotelling T2 test for functional data." Electronic Journal of Statistics (2013) Submitted

     
     

    Yamal JM, Guillaud M, Atkinson EN, Follen M, MacAulay C, Cantor S, Cox DD "Prediction using hierarchical data: applications for automated detection of cervical cancer." Statistical Analysis and Data Mining (2014) Submitted

     
     

    Ying JJ, Zhu H, Cox DD "Smoothing functional data with a Bayesian hierarchical model." Bayesian Analysis (2013) Submitted

     
     

    Yamal, J.M., Follen, M., Guillaud, M., Cox, D. "Classifying Tissue Samples from Measurements on Cells with Within-class Tissue Sample Heterogeneity." BiostatisticsIn Revision

     
     

    Swartz, R.J., Cox, D.D., Cantor, S.B., Davies, K. and Follen, M. "Inverse Decision Theory: Characterizing Losses for a Decision Rule with Applications in Cervical Cancer Screening." Journal of the American Statistical Association, 101 (2006) : 1-8.

     
     

    Cox, D.D., Chang, S.K., Dawood, M.Y., Staerkel, G., Utzinger, U., Richards-Kortum, R. and Follen, M. "Detecting a Signal from the Menstrual Cycle in Fluorescence Spectroscopy of the Cervix." Journal of Applied Spectroscopy, 57 (2003) : 67-72.Submitted

     
     

    Cox, D.D., Chang, S.K., Follen, M., Malpica, A., Utzinger, U., Staerkel, G., Atkinson, A.N., MacAulay, C. and Richards-Kortum, R. "Optimal Excitation Wavelengths for Discrimination of Cervial Neoplasia." IEEE Transactions on Biomedical Engineering, 49 (2002) : 1102-1111.

     
     

    Cox, D.D., Kloucek, P. and Reynolds, D. "Stochastic Relaxation of Variational Integrals with Nonattainable Infima." Proceedings of the European Conference on Numerical Mathematics and Advanced Applications (2003) Submitted

     
     

    Cox, D.D., Kloucek, P. and Reynolds, D. "The Non-Local Relaxation Of Non-Attainable Differential Inclusions Using a Subgrid Projection Method: One Dimensional Theory and Computations." SIAM J. Sci. Comp. (2003) Submitted

     
     

    Kim, T.Y., Park, J.S. and Cox, D.D. "A Fast Algorithms for Cross Validation of Best Linear Unbias Predictor." J. Comp Graph. Statst., 11 (2003)

     
     

    MacAulay,C., Richards-Kortum, R., Utzinger, U., Fedyk, A., Atkinson, E.N., Cox, D.D. and Follen, M. "Variation of Fluorescence Spectorscopy During the Menstrual Cycle." Optics Express, 10 (2002)

     
     

    Ndjeunga, J., Nelson, C. and Cox, D.D. "A Nearest Neighbor Test for Elliptical Symmetry." Journal of Computational and Graphical Statistics (2003) Submitted

     
     

    Swartz, R., Cox, D.D., Cantor, S., Davies, K. and Follen, M. "Inverse Decision Theory: Characterizing Losses for a Decision Rule with Applications in Cervial Cancer Screening." Journal of the American Statistical Association (2003) Submitted

     
     

    Swartz, R., West, L., Boiko, I., Malpica, A., Guillaud, M., Follen, M. and Cox, D.D. "Use of Nuclear Morphometry Characteristics to Distinguish Between Normal and Abnormal Cervical Glandular Histologies." Analytical Cellular Pathology (2003) In Press

     
     

    Whitney, P., Cox, D.D., Daly, D., Foote, H., McQuerry, D. and Sloughter, M. "Toward the Routine Analysis of Diverse Data Types." J. Computational & Graphical Statist (2003) Submitted

     
     

    Kim, T.Y., Parks, J.S. and Cox, D.D. "A Fast Algorithm for Cross Validation of BLUP." J. Comp Graph. Statistics (2002) In Press

     
     

    Reynolds, D., Kloucek, P. and Cox, D.D. "The Non-Local Relaxation of Non-attainable Differential Inclusions Using Subgrid Projection Method." Journal of Science Computer (2002) Submitted

     
     

    Swartz, R., West, L., Boiko, I., Malpica, A., Guillaud, M., Follen, M. and Cox, D.D. "Use of Nuclear Morphonmetry Characteristics to Distinguish Between Normal and Abnormal Cervical Clandular Histologies." Analytical Cellular PathologySubmitted

     
     

    West, L., Swartz, R., Boiko, I., MacAulay, C., Follen, M., Malpica, A. and Cox, D.D. "DNA Image Characteristics of Adenocarcinoma in Situ and Adenocarcinoma of the Cervix." American Journal of Obstetrics an dGynecology (2002) In Press

     
     Articles
     

    J. Yang, H. Zhu, D. Cox. "Smoothing functional data with a Bayesian hierarchical model." Bayesian Analysis in DecemberSubmitted

     
     

    Yamal, J.M., Follen, M., Guillaud, M., Cox, D.D. ". Classifying tissue samples from measurements on cells with within-class tissue sample heterogeneity." Biostatistics (2011) In Press

     
     

    Lee, J. and Cox, D.D. "Robust Smoothing: Smoothing Parameter Selection and Applications to Fluorescence Spectroscopy." Computational Statistics and Data Analysis, 54 (2010) : 3131-3143.

     
     

    Yamal, J.M., Cox, D.D., Atkinson, E.N. MacAulay, C., Price, R., and Follen, M. "Repeatability of tissue flourescence measurements for the detection of cervical intraepithelial neoplasia." Journal of Biomedical Optics Express, 1 (2010) : 641-657.

     
     

    Zhu, H., Vannucci, M. and Cox, D.D. "A Bayesian Hierarchical Model for Classification with Selection of Functional Predictors." Biometrics, 66 (2010) : 463-473.

     
     

    Calderon, C.P., Harris, N.C., Kiang, C.H., and Cox, D.D. "Analyzing Single-Molecule Manipulation Experiments." Journal of Molecular Recognition, 22 (5) (2009) : 356-365.

     
     

    Calderon, C.P., Harris, N.C., Kiang, C.H., and Cox, D.D. "Quantifying Multiscale Noise Sources in Single-Molecule Time Series." Journal of Physical Chemistry B, 113 (1) (2009) : 138-148.

     
     

    Yamal, J.M., Cox, D.D., Follen, M., Guillaud, M. "Classifying Tissue Samples from Measurements on Cells: Application in Cervical Neoplasia." Biometrics (2009) Submitted

     
     

    Calderon, C., Harris, N., Kiang, C. and Cox, D.D. "Analyzing Single Molecule Manipulation Experiments." Journal of Molecular Recognition. (2008) Submitted

     
     

    Cantor, S., Cardenas-Turanzas, M., Cox, D.D., Atkinson, E., Nogueras-Gonzalez, G., Beck, J., Follen, M. and Benedet, J. "Accuracy of Colposcopy in the Diagnostic Setting Compared to the Screening Setting." Obstetetrics and Gynecology, 111 (2008) : 7-14.

     
     

    Cox, D.D. and Lee, J. "Pointwise Testing with Functional Data Using theWestfall-Young Randomization Method." Biometrika, 95 (2008) : 621-634.

     
     

    Cox, D.D., Hardt, R. and Kloucek, P. "Convergence of Gibbs Measures Associated with Simulated Annealing." SIAM Journal on Mathematical Analysis, 39 (2008) : 1472-1496.

     
     

    Turner, J. and Cox, D.D. "An Adaptive Multiscale Simulation Algorithm." Journal of Chemical Physics (2009) Submitted

     
     

    Cantor, S., Cardenas-Turanzas, M., Cox, D.D., Atkinson, E., Nogueras-Gonzales, G., Beck, J., Follen, M. and Benedet, J. "Accuracy of Colposcopy in the Diagnostic Setting Compared to the Screening Setting." Obstetetrics and Gynecology (2007) In Press

     
     

    Cardenas-Turanzas, M., Freeburg, A., Benedict, J., Atkinson, E., Cox, D.D., Richards-Kortum, R., MacAulay, C., Follen, M. and Cantor, S. "The Clinical Effectiveness of Optical Spectroscopy for the in Vivo Diagnosis of Cervical Intraepithelial Neoplasia: Where are we?." Gynecologic Oncology (2007)

     
     

    Cong, X., Cox, D.D. and Cantor, S. "Bayesian Meta-Analysis of Papanicolaou Smear Accuracy." Gynecologic Oncology (2007)

     
     

    Cox, D.D. and Lee, J. "Pointwise Testing with Functional Data Using the Westfall-Young Randomization Method." Biometrika (2007) In Press

     
     

    Davies, K., Cox, D.D., Swartz, R., Cantor, S., Follen, M. "Inverse Decision Theory with Application to Screening and Diagnosis of Cervical Intraepithelial Neoplasia." Gynecologic Oncology (2007)

     
     

    Lee, J., Follen, M., MacAulay, C., Richards-Kortum, R., Pikkula, B., Serachitopol, D., Price, R. and Cox, D.D. "Sources of Variability in Fluorescence Spectroscopic Measurements in a Phase II Clinical Trial of 850 Patients." Gynecologic Oncology (2007)

     
     

    Pikkula, B., Shuhatovich, O., Price, R., Serachitopol, D., Follen, M., McKinnon, N., MacAulay, C., Richards-Kortum, R., Soo Lee, J., Neely Atkinson, E. and Cox, D.D. "Instrumentation as a Source of Variability in the Application of Fluorescence Spectroscopic Devices for Detecting Cervical Neoplasia." Journal of Biomedical Optics (2007)

     
     

    Davies, K., Cox, D.D., Swartz, R., Cantor, S.B. and Follen, M. "Inverse Decision Theory." Decision Analysis (2006) Submitted

     
     

    Xing, Y., Foy, M., Cox, D.D., Kuerer, H. M., Hunt, K. and Cormier, J.N. "Meta-Analysis of Sentinel Lymph Node Biopsy After Preoperative Chemotherapy in Patients with Breast Cancer." British Journal of Surgery, 93 (2006) : 539-546.

     
     

    Lee, J.S. and Cox, D.D. "Robust Smoothing: Smoothing Parameter Selection and Applications to Fluorescence Spectroscopy."  (2005) Submitted

     
     

    Lee, J.S., Shuhatovich, O., Pikkula, B., Price, R., Follen, M. MacKinnon, N., MacAulay, C., Richards-Kortum, R. and Cox, D.D. "Design and Preliminary Analysis of a Study to Assess Intra-Device and Inter-Device Variablity of Bluorescence Spectroscopy Instruments for Detecting Cervical Neoplasia." Gynecologic Oncology (2005) In Press

     
     

    Marin, N., MacKinnon N., MacAulay, C., Chang, S.K., Atkinson, E.N., Cox, D.D., Serachitopol, D., Follen, M. and Richards-Kortum, R. "Calibration Standards for Multi-Center Clincial Trials of Fluorescence Specroscopy For in Vivo Diagnosis." Journal of Biomedical Optics (2005) In Press

     
     

    Swartz, R., West, L., Boiko, I., Malpica, A., Guillaud, M., Follen, M. and Cox, D.D. "Classification Using Cumulative Log Odds With an Example in Quantitive Pathology of Adenocarcinoma of the Cervix." Gynecologic Oncology (2005) In Press

     
     

    Guillaud, M., Cox, D.D., Malica, A., Staerkel, G., Matisik, J., Van Niekirk, D., Adler-Storhz, K., Poulin, N., Follen, M. and MacAulay, C. "Quantitative Histopathological Analysis of Cervical Intra-Epithelial Neoplasia Sections: Methodological Issues." Cellular Oncology, 26 (2004) : 31-43.

     
     

    Gulliaud, M., Adler-Storthz, K., Malpica, A., Staerkel, G., Matistic, J., Van Niekirk, G., Cox, D.D., Poulin, N., Follen, M. and MacAulay, C. "Detections of HPV Infection in Cervical Epithelium by Texture Image Analysis." Cytometry - Part A (2004) Submitted

     
     

    Nath, A., Rivoire, K., Chang, S. and Cox, D.D. "Effect of Probe Pressure on Cervical Fluorescence Spectroscopy Measurements." J. Biomedical Optics, 9 (2004) : 523-533.

     
     

    Swartz, R., West, L., Boiko, I., Malpica, A., Guillaud, M., Follen, M. and Cox, D.D. "Classification Using Cumulative Log Odds With an Example in Quantitive Pathology of Adenocarcinoma of the Cervix." Statistics in Medicine (2004) Submitted

     
     

    Yamal, J.M., Cox, D.D., Hittelman, W., Boiko, I., Malpica, A., Guillaud, M., MacAulay, C., Follen, M. and Vlastos, A.T. "Quantitative Histopathology and Chromosome 9 Polysomy in a Clinical Trial of 4-HPR." Gynecologic Oncology (2004) Submitted

     
     Book reviews
     

    by Sheldon M Ross and Erol A Pek¿oz "A Second Course in Probability." Journal of the American Statistical Association. (2008)

     
     Refereed conference papers
     

    Guillaud, M., Cox, D.D., Adler-Storhz, K., Malpica, A., Staerkel, G., Matisik, J., Van Niekirk, D., Poulin, N., Follen, M. and MacAulay, C. "Exploratory Analysis of Quantitative Histopathology of Cervical Intra-Epithelial Neoplasia: Objectivity, Reproducibility Malignancy-associated Changes and Human Papillomavirus." Cytometry (2003) Submitted

     
     Conference papers
     

    Lee, J.S. and Cox, D.D. "Randomization Tests for Functional Data Based on Adaptive Truncation." Proceedings of the Interface 2005 (2005)

     
     

    Cox, D.D., Kloucek, P. and Reynolds, D.R. "On the Asymptotically Stochastic Computational Modeling of Microstructures." Future Generation Computer System on Modern Numerical Algrithms (2003) Submitted

     
     

    "ANOVA for Functional Data."  (2003/Sept) Submitted

     
     

    "Best Unbiased Prediction for Gaussian and Non-Gaussian Processes."  (2002) Submitted

     
     

    "Estimating the Integral of a Nongaussian Random Function."  (2003/Aug) Submitted

     
     

    "Inverse Decision Theory: Making Inferences About Losses from Observed Behavior."  (2003/April) Submitted

     
     

    "Randomization Based Methods for Functional ANOVA."  (2003/Sept) Submitted

     
     Other
     

    Cox, D.D., Chang, S.K., Dawood, M.Y., Staerkel, G., Utzinger, U., Richards-Kortum, R. and Follen, M. "Detecting a Signal From the Menstrual Cycle in Fluorescence Spectroscopy of the Cervix." Journal of Applied Spectroscopy (2001)

     
     

    Cox, D.D., Kloucke, P. and Reynolds, D. "The Non-Local Relaxation of Non-Attainable Differential Inclusions Using Subgrid Projection Method." Journal of Nonlinear Science (2001)

     
     

    Cox, D.D., Swartz, R., Boiko, I., Mailpica, A., Guillaud, M. and Follen, M. "Classifying Populations from Samples Using Quantitative Pathology." Biometrics (2001)

     
     

    Baggerly, K. and Picard, R. "Exponential Convergence of Adaptive Importance Sampling for Markov Chains." Journal of Applied Probability, 37 (2000) : 342-358.

     
     

    Cox. D.D. "Review of "Rank-Deficient and Ill-Posed Problems: Numerical Aspects of Linear Inversion" by Per Christian Hansen." Journal of the American Statistical Association (1999)

     
     

    Follen, M., Pandy, D., Atkinson, E., Poulin, N., MacAulay, C. and Richards-Kortum, R. "Fluorescence Spectroscopy, Quantitative Pathology, and Classification of Tissue." Computing Science and Statistics, 31 (1999) : 110-117.

     
     

    Kollman, C., Baggerly, K. and Picard, R. "Adaptive Importance Sampling on Discrete Markov Chains." Annals of Applied Probability, 9 (1999) : 391-412.

     
    Presentations
     Invited Papers
     

    "ANOVA for Funcational Data." Banff International Research Station Workshop on Statistics and Regularization, Canada. (September, 2003)

     
     

    "Best Unbiased Prediction for Gaussian and Non-Gaussian Processes." Proceedings of the First Lehmann Symposium, Guanajuato, Mexico. (May 23-25, 2002)

     
     

    "Randomization Based Methods for Functional ANOVA." Lack-of-Fit Workshop, Department of Statistics, Texas A&M. (September, 2003)

     
     

    "Topics in Environmental Statistics." JSM, San Francisco, CA. (August, 2003)

     
     

    "Classifying Population from Samples Using Quantitative Pathology." 2002 Proceedings of the American Statistical Association, Biometrics Section, Alexandria, VA. (2002) With Swartz, R., West, L., Boiko, I., Malpica, A., Guillaud, M., Follen, M.

     
     

    "The Computational Modeling of Crystalline Materials Using a Stochastic Variational Principle." Future Generation Computer System on Modern Numerical Algorithms, With Kloucek, P., Reynolds, D.R.

     
     Invited Talks
     

    "Spoke at the 2012 Conference of Texas Statisticians." Lamar University Campus, Beaumont, Texas. (03/02/2012)

     
     

    "Robust Cross-Validation Using and L1 Criterion." Interface 2010 Meeting, Seattle, WA. (June 16, 2010)

     
     

    "Bayesian Models for Covariance Functions." Colloquium, Department of Statistical Science, Duke University, (March 6, 2009)

     
     

    "Convergence of Gibbs Measures that Arise in Simulated Annealing." Department of Mathematics, University of Delaware, (November 12, 2009)

     
     

    "Principles of Bayesian Functional Data Analysis." Colloquium, Statistics Group, Department of Food and Resource Economics, University of Delaware, (November 13, 2009)

     
     

    "Covariance Prior for Bayesian Functional Data Analysis." Department of Statistics, Carnegie Mellon University, (March 5,2008)

     
     

    "Pointwise Testing with Functional Data Using theWestfall-Young RandomizationMethod." Colloquium, Department of Statistical Sciences of Baylor University, Houston, TX. (February 29, 2008)

     
     ¿Convergence of Gibbs Measures Associated with Simulated Annealing,¿ Colloquium, Op- erations Research Group, Department of Mechanical Engineering, University of Texas, Austin, Texas, November 16, 2007.
     
     

    "Useful Priors for Covariance Operators." Workshop for Construction and Properties of Bayesian Nonparametric Regression Models, Isaac Newton Institute for Mathematical Sciences, Cambridge UK. (August 7, 2007)

     
     

    "Bayesian Inverse Decision Theory." Joint Statistics Meeting, Toronto, Canada. (August 10, 2004)

     
     

    "Bayesian Methods in Health and Health Policy." JSM Conference, San Francisco, CA. (August 2003)

     
     

    "Best Unbiased Prediction for Gaussian and Non-Gaussian Processes." First Erich Lehmann Symposium, Guanajuato, Mexico. (May 25, 2002)

     
     

    "Estimating the Integral of a Nongaussian Random Function." Summer Research Conference in Statistics, Natchez, Mississippi. (June 3, 2002)

     
     

    "Inverse Decision Theory: Making Inferences About Losses from Observed Behavior." Houston Area Chapter of the American Statistical Association, (April 8, 2003)

     
     

    "Resampling Methods for Multiple Comparisons of Randomizaiton Tests." Conference of Texas Statisticians, Rice University, Houston Texas. (April 5, 2002)

     
     Other
     

    "Comparison of an Ocean Circulation Model with Observation Data (Invited Presentation)." Statistical Analysis of Computer Code Output Workshop, Gregynog, United Kingdom. (April 11, 2000)

     
     

    "Bayesian Regression with Autoregressive Errors: Some Problems and Fixes." Summer Research Conference on Statistics, Mountain View, AR. (June 15, 1999)

     
     

    "Fluorescence Spectroscopy, Quantitative Pathology, and Classification of Tissue." 31st Symposium on the Interface: Models, Predictions, and Computing, Schaumburg, IL. (June 10, 1999)

     
     

    "Spatial-Temporal Modeling of Vector Valued Data Using Gradient Processes: An Application to Wind Fields." Probability and Statistics Seminar, Department of Mathematics, University of Colorado , Denver, CO. (November 23, 1999)

     
     

    "Data Mining: Methodology and Case Studies." Spring Research Conference on Statistics in Industry and Technology, Santa Fe, NM. (June 3, 1998)

     
    Editorial Positions
     Associate Editor, Bayesian Analysis. (2009 - 2009)

     Associate Editor, Scandinavian Journal of Statistics. (2009 - 2009)

    Supervised Theses & Dissertations
     Richard J. Swartz, Ph.D Applications of Bayesian Sequential Decision Theory to Medical Decision Making. (2002) (Committee Member)

     Kalatu Davies, Ph.D Inverse Decision Theory with Medical Applications. (2004) (Thesis or Dissertation Director)

     Kalatu Davies, Ph.D Inverse Decision Theory with Medical Applications. (2005) (Thesis or Dissertation Director)

     Meichun Ding, Ph.D Bayesian Optimal Design for Phase II Screening Trials. (2005) (Co-Director)

     Jong Soo Lee, Ph.D Aspects of Functional Data Inference and Its Applications. (2005) (Thesis or Dissertation Director)

     Alena Scott, Ph.D. Denoising by Wavelet Thresholding Using Multivariate Minimum Distance Partial Density Estimation. (2006) (Committee Member)

     Chad Bhatti, Ph.D. Statistical Models for Intraday Trading Dynamics. (2006) (Thesis or Dissertation Director)

     Jose-Miguel Yamal, Ph.D. Multilevel Classification. (2006) (Thesis or Dissertation Director)

     Jose-Miguel Yamal, Ph.D. Multilevel Classification. (2007) (Thesis or Dissertation Director)

     Chad Bhatti, Ph.D. Statistical Models for Intraday Trading Dynamics. (2007) (Thesis or Dissertation Director)

     Jong Soo Lee, Ph.D Hypothesis Testing with Functional Data. (Thesis or Dissertation Director)

     Jesse Turner, Ph.D Multiscale Modeling of Cellular Chemistry. (Co-Director)

     Chad Bhatti, Ph.D Point Process Modeling of High Frequency Financial Data. (Thesis or Dissertation Director)

     Jose-Miguel Yamal, Ph.D Multilevel Classification. (Thesis or Dissertation Director)

    Awards, Prizes, & Fellowships
     Presidential Mentoring Award, Rice University

     Fellow, American Statistical Association, American Statistical Association (1998)

    Positions Held
     Member, American Statistical Association. (2006 - 2006)

     Fellow, American Statistical Association. (2002 - 2002)