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Scholarly Interest Report
         
Gang Bao
Professor
Foyt Family Professor of Bioengineering
 
e-mail:Gang.Bao@rice.edu
 
  • B.Sc. Mechanical Engineering (1976) Shandong University
  • M.Sc. Applied Mechanics (1981) Shandong University
  • Ph.D. Applied Mathematics (1987) Lehigh University
 
Primary Department
   Department of Bioengineering
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Selected Publications
 Refereed articles
 

S. Suzuki, G. Sargent, B. Illek, H. Fischer, A. Esmaeili-Shandiz, M. J. Yezzi, A. Lee, Y. Yang, S. Kim, P. Renz, Z. Qi, J. Yu, M. O. Muench, A. I. Beyer, A. O. Guimarães, L. Ye, J. Chang, E. J. Fine, T. J. Cradick, G. Bao, M. Rahdar, M. H. Porteus, T. Shuto, H. Kai, Y. W. Kan, D. C. Gruener*, “TALENs Facilitate Single-step Seamless SDF Correction of F508del CFTR in Airway Epithelial Submucosal Gland Cell-derived CF-iPSCs”, Molecular Therapy Nucleic Acids, 5, e273 (2016). 

 
 

A. Hendel, E. J. Fine, G. Bao, M. H. Porteus*, “Quantifying On and Off-Target Genome Editing”, Trends in Biotechnology, 33, 132-40 (2015).

 
 

E. J. Fine, C. Appleton, M. Brown, H. Deshmukh and G.Bao*, “Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human HEK-293T cells: a first step towards AAV packaging”, Scientific Reports, 5, 10777 (2015).

 
 

J. Corrigan-Curay, M. O’Reilly, D.B. Kohn, P.M. Cannon, G. Bao et al, “Genome Editing Technologies: Defining a Path to Clinic”, Molecular Therapies, 23, 796-806 (2015). 

 
 

J. Giraldo-Vela, W. Kang, R. McNaughton, X. Zhang, B. Wile, A. Tsourkas, G. Bao, H. Espinosa*, “Single-Cell Detection of mRNA Expression Using Nanofountain-Probe Electroporated Molecular Beacons”, Small, 11, 2386-91 (2015).

 
 

J. Zhao, I. Akinsanmi1, D. Arafat, T. J. Cradick, C. M. Lee, S. Banskota, G. Bao, and G. Gibson. A Burden of Rare Variants Associated with Extremes of Gene Expression in Human Peripheral Blood, The American J. Human Genetics, in press (2015).

 
 

K. Ban, PhD, B. Wile, K. W. Cho, S. Kim, M. K. Song, J. Singer, A. Syed, S. P. Yu, M. Wagner, G. Bao* and Y. S. Yoon*, “Non-genetic purification of ventricular cardiomyocytes from differentiating embryonic stem cells through molecular beacons targeting a ventricle-specific transcription factor”, Stem Cell Reports, 5, 1239-49 (2015).

 
 

L. Minati, V. Antonini, C. Pederzolli, M. Dalla Serra, G. Bao, G. Speranza*, “Combinatorial plasma polymerization: C-based films”, Encyclopedia of Plasma Technology, in press (2015).

 
 

M. Aouida, A. Eid, Z. Ali, T. J. Cradick, H. Deshmukh, A. Atef, D. B. AbuSamra, C. M. Lee, S. Z. Gadhoum, J. S. Merzaban, G. Bao and M. M. Mahfouz*, “Efficient fdCas9 Synthetic Endonuclease with Improved Specificity for Precise Genome Engineering”, PLoS One, 10, e0133373 (2015). 

 
 

M. Müller, C. M. Lee, G. Gasiunas, T. Davis, T. J. Cradick, V. Siksnys, G. Bao, C. Mussolino, T. Cathomen, “Streptococcus thermophilus CRISPR-Cas9 systems enable specific editing of the human genome”, Molecular Therapy, 2015 Dec 14. doi: 10.1038/mt.2015.218. [Epub ahead of print] (2015).

 
 

C.A. Quinto, P. Mohindra, S. Tong, G. Bao*, “Multifunctional Superparamagnetic Iron Oxide Nanoparticles for Combined Chemotherapy and Hyperthermia Cancer Treatment”, Nanoscale, 7, 12728-12736 (2015).

 
 

N. Hoshyar, S. Gray, H. Han, G. Bao*, “The Effect of Nanoparticle Size on In vivo Pharmacokinetics and Cellular Interaction”, Nanomedicine, in press (2015). 

 
 

R. Jhaa, B. Wile, Q. Wu, A. H. Morris, K. O. Maher, M. B. Wagner, G. Bao*, C. Xu*, “Molecular Beacon-based Detection and Isolation of Working-type Cardiomyocytes Derived from Human Pluripotent Stem Cells”, Biomaterials 50, 176-85 (2015).

 
 

R. N. Cottle, C. M. Lee, D. Archer and G. Bao*, “Controlled delivery of β-globin-targeting TALENs and CRISPR/Cas9 into mammalian cells for genome editing using microinjection” Scientific Reports, 5, 16031 (2015).

 
 

S. L. Zhang*, H. J. Gao* and G. Bao*.  “Mechanics of Endocytosis”, ACS Nano, 9, 8655-71 (2015).

 
 

T. A. Meyer, C. A. Quinto, G. Bao*, “Controlling Iron Oxide Nanoparticle Clustering Using Dual Solvent Exchange Coating Method”, IEEE Magnetics Letters, in press (2015).

 
 

Y. Yang, J. Ran, L. Sun, X. Sun, Y. Luo, B. Yan, Tala, M. Liu, D. Li, L. Zhang, G. Bao*, J. Zhou*, “CYLD regulates noscapine activity in acute lymphoblastic leukemia via a microtubule-dependent mechanism”, Theranostics, 5, 656-66 (2015)

 
Presentations
 Invited Talks
 

ASME 2015 IMECE, Houston, TX, Nov. 18, 2015.  “Bioengineering and Precision Medicine: Opportunities and Challenges”, invited Plenary Lecture.

 
 

 Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, Nov. 30, 2015. “Design and Optimization of Engineered Nucleases for Treating Single-gene Disorders Using Genome Editing”, invited lecture.

 
 

Center for Human Immunobiology, Baylor College of Medicine, Houston, TX, Sept 11, 2015. “Engineered Nucleases Based Genome Editing for Treating Single-gene Disorders”, invited seminar.

 
 

Department of Biomedical Engineering, University of California at Davis, Davis, CA, Sept 18, 2015. “Engineered Nucleases Based Genome Editing for Treating Single-gene Disorders”, invited seminar

 
 

Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, Sept 15, 2015. “Engineered Nucleases Based Genome Editing for Treating Single-gene Disorders”, invited seminar.

 
 

Houston Methodist Research Institute, Houston, TX, August 28, 2015. “Engineered Nucleases Based Genome Editing for Treating Single-gene Disorders”, invited seminar

 
 

Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX, Nov 3rd, 2015. “Engineered Nucleases Based Genome Editing for Treating Single-gene Disorders”, invited seminar.

 
 

The Frist International Workshop on Rare Diseases, Riyadh, Saudi Arabia, March 1-2, 2015. “Engineered-nuclease based Genome Editing for Treating Single-gene Disorders”, invited lecture.

 
 

Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Hong Kong, Dec. 18, 2015. “Engineering Imaging Probes and Molecular Machines for Nanomedicine”, invited seminar. 

 
 

 National Center for Nanoscience and Technology of China, Beijing, China, January 15, 2015. “Engineering Molecular Probes and Machines for Nanomedicine”, invited seminar.

 
 

Department of Chemistry, Oregon State University, Corvallis, OR, Feb 23, 2015. “Engineering Molecular Probes and Machines for Nanomedicine”, invited seminar.

 
 

Division of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, Nov. 30, 2015. “Engineering Multifunctional Nanoparticles for Disease Detection and Treatment”, invited lecture

 
 

The 6th International Conference on Nanoscience and Technology, Beijing, China, Sept 3rd, 2015, “Engineering Nano-scissors for Genome Editing based Treatment of Single-gene Disorders”, invited talk.

 
 

International Symposium on Translational Nanomedicine, Guangzhou, China, January 8-10, 2015. “Genome Editing for Treating Single-gene Disorders”, invited talk.

 
 

 Department of Engineering, University of Cambridge, Cambridge, UK, Oct 14, 2015. “Multifunctional Magnetic Nanoparticles for Drug Delivery and Cell Tracking”, invited seminar.

 
 

The Frist International Workshop on Rare Diseases, Riyadh, Saudi Arabia, March 1-2, 2015. “Nanomedicine Approaches for Disease Detection and Treatment”, invited lecture

 
 

Department of Engineering Science, University of Oxford, Oxford, UK, Oct 13, 2015. “Nanomedicine Approaches for Disease Detection and Treatment”, invited seminar.

 
 

GEM4 Summer School on Mechanobiology of the Brain, Carnegie Mellon University, Pittsburgh, PA, June 26, 2015. “Nanomedicine and Genome Editing”, invited lecture.

 

 
 

Symposium on New Frontiers In Gene Editing, Molecular Medicine Tri-Conference, San Francisco, CA, Feb 19-20, 2015. “Nuclease-Based Gene Correction for Treating Single Gene Disorders”, invited talk.

 
 Keynote Speaker
 

The ASME 2015 4th Global Congress on NanoEngineering for Medicine and Biology, Minneapolis, MN, April 19-22, 2015. “Internalization of Magnetic Nanoparticles for Drug Delivery and Cell Tracking”, invited keynote lecture.

 
Editorial Positions
 Editor, Interdisciplinary Bio Central . (2009 - 2015)

 Member of the Editorial Board, Nanotechnology, Science and Applications . (2009 - 2015)

 Member of the Editorial Board, Technology. (2013 - 2015)

 Member of the Editorial Board, Acta Biomaterialia . (2004 - 2015)

 Member of the Editorial Board, Materials Science and Engineering C . (2007 - 2015)

 Member of the Editorial Board, Nanomedicine (Future Medicine Group) . (2006 - 2015)

 Member of the Editorial Board, Journal of the Mechanical Behaviour of Biomedical Materials . (2008 - 2015)